STRINGSTRING
aftA aftA embC embC aftB aftB aftC aftC Cgl0189 Cgl0189 crtEb crtEb Cgl1897 Cgl1897 Cgl2689 Cgl2689 wbbL wbbL Cgl2880 Cgl2880 Cgl1486 Cgl1486
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
aftAMembrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases (By similarity). (677 aa)    
Predicted Functional Partners:
embC
Probable arabinosyltransferase, membrane protein.
  
  
 0.998
aftB
Putative membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl- phospho-arabinose (DPA) to the arabinan domain to form terminal beta- (1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. Belongs to the AftB family.
   
  
 0.985
aftC
Putative secreted protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. Belongs to the glycosyltransferase 87 family.
      
 0.980
Cgl0189
PUTATIVE OXIDOREDUCTASE.
     
 0.914
crtEb
LYCOPENE ELONGASE.
      
 0.880
Cgl1897
Putative membrane protein.
      
 0.842
Cgl2689
Conserved hypothetical protein.
   
  
 0.796
wbbL
Putative rhamnosyl transferase WbbL.
      
 0.792
Cgl2880
4-hydroxybenzoate polyprenyltransferase or related prenyltransferase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5-phosphoribose (DPPR).
     
 0.687
Cgl1486
Short-chain dehydrogenase/reductase.
  
  
 0.655
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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