node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl0294 | Cgl0295 | cg0354 | cg0355 | THIOREDOXIN-RELATED PROTEIN, secreted. | Pyrophosphohydrolase. | 0.975 |
Cgl0294 | Cgl0296 | cg0354 | cg0356 | THIOREDOXIN-RELATED PROTEIN, secreted. | Putative serine protease, membrane protein. | 0.701 |
Cgl0294 | glxR | cg0354 | cg0350 | THIOREDOXIN-RELATED PROTEIN, secreted. | TRANSCRIPTIONAL REGULATOR, CRP/FNR FAMILY; Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Involved in the regulation of gntP and gntK genes, which are involved in gluconate metabolism. May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes. It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole [...] | 0.534 |
Cgl0294 | nth | cg0354 | cg0353 | THIOREDOXIN-RELATED PROTEIN, secreted. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.844 |
Cgl0295 | Cgl0294 | cg0355 | cg0354 | Pyrophosphohydrolase. | THIOREDOXIN-RELATED PROTEIN, secreted. | 0.975 |
Cgl0295 | Cgl0296 | cg0355 | cg0356 | Pyrophosphohydrolase. | Putative serine protease, membrane protein. | 0.706 |
Cgl0295 | glxR | cg0355 | cg0350 | Pyrophosphohydrolase. | TRANSCRIPTIONAL REGULATOR, CRP/FNR FAMILY; Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Involved in the regulation of gntP and gntK genes, which are involved in gluconate metabolism. May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes. It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole [...] | 0.525 |
Cgl0295 | nth | cg0355 | cg0353 | Pyrophosphohydrolase. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.926 |
Cgl0296 | Cgl0294 | cg0356 | cg0354 | Putative serine protease, membrane protein. | THIOREDOXIN-RELATED PROTEIN, secreted. | 0.701 |
Cgl0296 | Cgl0295 | cg0356 | cg0355 | Putative serine protease, membrane protein. | Pyrophosphohydrolase. | 0.706 |
Cgl0296 | arc | cg0356 | cg1691 | Putative serine protease, membrane protein. | ATPases of the AAA+ class. | 0.741 |
Cgl0296 | glpK | cg0356 | cg3198 | Putative serine protease, membrane protein. | GLYCEROL KINASE; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.475 |
Cgl0296 | glxR | cg0356 | cg0350 | Putative serine protease, membrane protein. | TRANSCRIPTIONAL REGULATOR, CRP/FNR FAMILY; Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Involved in the regulation of gntP and gntK genes, which are involved in gluconate metabolism. May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes. It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole [...] | 0.471 |
Cgl0296 | lppS | cg0356 | cg2720 | Putative serine protease, membrane protein. | Secreted lipoprotein ErfK/YbiS/YcfS/YnhG family; May play a role in cell wall biology; Belongs to the YkuD family. | 0.569 |
Cgl0296 | nth | cg0356 | cg0353 | Putative serine protease, membrane protein. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.659 |
Cgl0296 | purH | cg0356 | cg0984 | Putative serine protease, membrane protein. | 5'-PHOSPHORIBOSYL-5-AMINOIMIDAZOLE-4- CARBOXYLASE. | 0.455 |
Cgl0296 | rlmN | cg0356 | cg2214 | Putative serine protease, membrane protein. | Predicted Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.583 |
Cgl0296 | secA | cg0356 | cg0868 | Putative serine protease, membrane protein. | PREPROTEIN TRANSLOCASE SUBUNIT SECA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.725 |
arc | Cgl0296 | cg1691 | cg0356 | ATPases of the AAA+ class. | Putative serine protease, membrane protein. | 0.741 |
arc | glpK | cg1691 | cg3198 | ATPases of the AAA+ class. | GLYCEROL KINASE; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.964 |