node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceE | lpd | cg2466 | cg0441 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | DIHYDROLIPOAMIDE DEHYDROGENASE; Lipoamide dehydrogenase is an essential component of the pyruvate dehydrogenase (PDH) and 2-oxoglutarate dehydrogenase (ODH) complexes. Catalyzes the reoxidation of dihydrolipoyl groups which are covalently attached to the lipoate acyltransferase components (E2) of the complexes. Also catalyzes a reversible NADH:NAD(+) transhydrogenation, and is able to transfer electrons from NADH to various redox-active compounds and quinones. May be involved in quinone redox cycling in C.glutamicum. | 0.996 |
aceE | odhA | cg2466 | cg1280 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | 2-OXOGLUTARATE DEHYDROGENASE; Catalyzes the E1 and E2 reactions as part of 2-oxoglutarate dehydrogenase (ODH) activity, to convert 2-oxoglutarate to succinyl-CoA and CO(2). OdhA has reductase activity with 2-oxoglutarate but does not react with pyruvate, and also displays transsuccinylase but no transacetylase activity. Since OdhA is not lipoylated, the succinyltransferase activity of its E2 domain is dependent on lipoyl residues of the acetyltransferase AceF. | 0.969 |
aceE | sucB | cg2466 | cg2421 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE; Is essential for both 2-oxoglutarate dehydrogenase (ODH) and pyruvate dehydrogenase (PDH) activities, but AceF has exclusively transacetylase (and no transsuccinylase) activity. The lipoyl residues required for ODH activity are likely provided by AceF. Belongs to the 2-oxoacid dehydrogenase family. | 0.996 |
fadE | lpd | cg0346 | cg0441 | GLUTARYL-COA DEHYDROGENASE. | DIHYDROLIPOAMIDE DEHYDROGENASE; Lipoamide dehydrogenase is an essential component of the pyruvate dehydrogenase (PDH) and 2-oxoglutarate dehydrogenase (ODH) complexes. Catalyzes the reoxidation of dihydrolipoyl groups which are covalently attached to the lipoate acyltransferase components (E2) of the complexes. Also catalyzes a reversible NADH:NAD(+) transhydrogenation, and is able to transfer electrons from NADH to various redox-active compounds and quinones. May be involved in quinone redox cycling in C.glutamicum. | 0.915 |
fadE | sucB | cg0346 | cg2421 | GLUTARYL-COA DEHYDROGENASE. | DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE; Is essential for both 2-oxoglutarate dehydrogenase (ODH) and pyruvate dehydrogenase (PDH) activities, but AceF has exclusively transacetylase (and no transsuccinylase) activity. The lipoyl residues required for ODH activity are likely provided by AceF. Belongs to the 2-oxoacid dehydrogenase family. | 0.912 |
gdh | glnA | cg2280 | cg2429 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE SYNTHETASE I. | 0.959 |
gdh | glnA2 | cg2280 | cg2447 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE SYNTHETASE 2. | 0.931 |
gdh | gltB | cg2280 | cg0229 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | 0.999 |
gdh | lpd | cg2280 | cg0441 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | DIHYDROLIPOAMIDE DEHYDROGENASE; Lipoamide dehydrogenase is an essential component of the pyruvate dehydrogenase (PDH) and 2-oxoglutarate dehydrogenase (ODH) complexes. Catalyzes the reoxidation of dihydrolipoyl groups which are covalently attached to the lipoate acyltransferase components (E2) of the complexes. Also catalyzes a reversible NADH:NAD(+) transhydrogenation, and is able to transfer electrons from NADH to various redox-active compounds and quinones. May be involved in quinone redox cycling in C.glutamicum. | 0.861 |
gdh | odhA | cg2280 | cg1280 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 2-OXOGLUTARATE DEHYDROGENASE; Catalyzes the E1 and E2 reactions as part of 2-oxoglutarate dehydrogenase (ODH) activity, to convert 2-oxoglutarate to succinyl-CoA and CO(2). OdhA has reductase activity with 2-oxoglutarate but does not react with pyruvate, and also displays transsuccinylase but no transacetylase activity. Since OdhA is not lipoylated, the succinyltransferase activity of its E2 domain is dependent on lipoyl residues of the acetyltransferase AceF. | 0.952 |
gdh | putA | cg2280 | cg0129 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | PROLINE DEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE. | 0.954 |
gdh | sucB | cg2280 | cg2421 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE; Is essential for both 2-oxoglutarate dehydrogenase (ODH) and pyruvate dehydrogenase (PDH) activities, but AceF has exclusively transacetylase (and no transsuccinylase) activity. The lipoyl residues required for ODH activity are likely provided by AceF. Belongs to the 2-oxoacid dehydrogenase family. | 0.418 |
glnA | gdh | cg2429 | cg2280 | GLUTAMINE SYNTHETASE I. | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.959 |
glnA | glnA2 | cg2429 | cg2447 | GLUTAMINE SYNTHETASE I. | GLUTAMINE SYNTHETASE 2. | 0.922 |
glnA | gltB | cg2429 | cg0229 | GLUTAMINE SYNTHETASE I. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | 0.994 |
glnA | lpd | cg2429 | cg0441 | GLUTAMINE SYNTHETASE I. | DIHYDROLIPOAMIDE DEHYDROGENASE; Lipoamide dehydrogenase is an essential component of the pyruvate dehydrogenase (PDH) and 2-oxoglutarate dehydrogenase (ODH) complexes. Catalyzes the reoxidation of dihydrolipoyl groups which are covalently attached to the lipoate acyltransferase components (E2) of the complexes. Also catalyzes a reversible NADH:NAD(+) transhydrogenation, and is able to transfer electrons from NADH to various redox-active compounds and quinones. May be involved in quinone redox cycling in C.glutamicum. | 0.834 |
glnA | odhA | cg2429 | cg1280 | GLUTAMINE SYNTHETASE I. | 2-OXOGLUTARATE DEHYDROGENASE; Catalyzes the E1 and E2 reactions as part of 2-oxoglutarate dehydrogenase (ODH) activity, to convert 2-oxoglutarate to succinyl-CoA and CO(2). OdhA has reductase activity with 2-oxoglutarate but does not react with pyruvate, and also displays transsuccinylase but no transacetylase activity. Since OdhA is not lipoylated, the succinyltransferase activity of its E2 domain is dependent on lipoyl residues of the acetyltransferase AceF. | 0.524 |
glnA | putA | cg2429 | cg0129 | GLUTAMINE SYNTHETASE I. | PROLINE DEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE. | 0.924 |
glnA2 | gdh | cg2447 | cg2280 | GLUTAMINE SYNTHETASE 2. | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.931 |
glnA2 | glnA | cg2447 | cg2429 | GLUTAMINE SYNTHETASE 2. | GLUTAMINE SYNTHETASE I. | 0.922 |