STRINGSTRING
sdhCD sdhCD sdhA sdhA sdhB sdhB sucD sucD sucC sucC gabD3 gabD3 gabD2 gabD2 fum fum actA actA gabD1 gabD1 ctaE ctaE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhCDSuccinate dehydrogenase CD. (257 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase A.
 
 0.999
sdhB
Succinate dehydrogenase B.
 
 
 0.999
sucD
SUCCINYL-COA SYNTHETASE ALPHA SUBUNIT; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.921
sucC
SUCCINYL-COA SYNTHETASE BETA SUBUNIT; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.916
gabD3
SUCCINATE-SEMIALDEHYDE DEHYDROGENASE (NADP+); Belongs to the aldehyde dehydrogenase family.
     
  0.900
gabD2
PUTATIVE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE (NADP+); Belongs to the aldehyde dehydrogenase family.
     
  0.900
fum
FUMARATE HYDRATASE; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 
  0.900
actA
BUTYRYL-COA:ACETATE COENZYME A TRANSFERASE.
   
 
  0.900
gabD1
PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE OXIDOREDUCTASE; Belongs to the aldehyde dehydrogenase family.
     
  0.900
ctaE
CYTOCHROME C OXIDASE SUBUNIT 3.
   
  
 0.878
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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