STRINGSTRING
hemD hemD hemC hemC hemB hemB hemA hemA hemL hemL hemE hemE cobA cobA hemY hemY hemN hemN ccsB ccsB cobL cobL
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemDUROPORPHYRINOGEN III SYNTHASE/METHYLTRANSFERASE. (598 aa)    
Predicted Functional Partners:
hemC
PORPHOBILINOGEN DEAMINASE; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
hemB
DELTA-AMINOLEVULINIC ACID DEHYDRATASE; Belongs to the ALAD family.
 
 0.999
hemA
GLUTAMYL-TRNA REDUCTASE; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.997
hemL
GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE.
 
  
 0.971
hemE
UROPORPHYRINOGEN DECARBOXYLASE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.965
cobA
UROPORPHYRINOGEN III SYNTHASE/METHYLTRANSFERASE; Belongs to the precorrin methyltransferase family.
 
 
0.949
hemY
PUTATIVE PROTOPORPHYRINOGEN OXIDASE; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
  
 0.889
hemN
PUTATIVE ANAEROBIC COPROPORPHYRINOGEN III OXIDASE; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.886
ccsB
Cytochrome c assembly membrane protein.
 
    0.868
cobL
PRECORRIN-6Y C5,15-METHYLTRANSFERASE (DECARBOXYLATING).
  
  
 0.858
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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