STRINGSTRING
menA menA Cgl0453 Cgl0453 ubiE ubiE menB menB menD menD menE menE hisH hisH idsA idsA ispF ispF Cgl0449 Cgl0449 Cgl2910 Cgl2910
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
menA1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (298 aa)    
Predicted Functional Partners:
Cgl0453
PUTATIVE 5-DEHYDRO-4-DEOXYGLUCARATE DEHYDRATASE; Belongs to the DapA family.
   
  
 0.961
ubiE
UBIQUINONE/MENAQUINONE BIOSYNTHESIS METHYLTRANSFER; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
    
 0.928
menB
DIHYDROXYNAPHTHONIC ACID SYNTHASE; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
  
 0.861
menD
2-OXOGLUTARATE DECARBOXYLASE; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
  
 0.840
menE
O-SUCCINYLBENZOIC ACID-COA LIGASE.
 
   
 0.788
hisH
IMIDAZOLEGLYCEROL-PHOSPHATE SYNTHASE, AMIDOTRANSFERASE; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
   
  
 0.728
idsA
PUTATIVE GERANYLGERANYL PYROPHOSPHATE SYNTHASE; Belongs to the FPP/GGPP synthase family.
  
  
 0.675
ispF
2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
   
  
 0.672
Cgl0449
PUTATIVE GLYCOSYLTRANSFERASE.
  
    0.667
Cgl2910
PYRUVATE KINASE-LIKE PROTEIN.
   
  
 0.637
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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