STRINGSTRING
Cgl0617 Cgl0617 Cgl0616 Cgl0616 Cgl1166 Cgl1166 Cgl0038 Cgl0038 dnaE2 dnaE2 dnaN dnaN recN recN lexA lexA dnaX dnaX fkpA fkpA recA recA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cgl0617Polymerase involved in DNA repair. (530 aa)    
Predicted Functional Partners:
Cgl0616
Conserved hypothetical protein.
 
  
 0.999
Cgl1166
DNA repair exonuclease.
   
 
 0.976
Cgl0038
PUTATIVE IRON-SIDEROPHORE UPTAKE SYSTEM ATP-BINDIN.
      
 0.965
dnaE2
PUTATIVE DNA POLYMERASE III ALPHA CHAIN; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.959
dnaN
DNA POLYMERASE III, BETA SUBUNIT; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.926
recN
DNA REPAIR PROTEIN RECN; May be involved in recombinational repair of damaged DNA.
  
  
 0.776
lexA
PUTATIVE LEXA REPRESSOR TRANSCRIPTION REGULATOR PROTEIN; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
 
 0.765
dnaX
PUTATIVE DNA POLYMERASE III, DELTA' SUBUNIT.
   
 
 0.650
fkpA
PROBABLE FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOME; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family.
  
 
 
 0.640
recA
DNA RECOMBINATION/REPAIR; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.637
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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