node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl0616 | Cgl0617 | cg0713 | cg0714 | Conserved hypothetical protein. | Polymerase involved in DNA repair. | 0.999 |
Cgl0616 | dinP | cg0713 | cg2355 | Conserved hypothetical protein. | Nucleotidyltransferase/DNA polymerase involved in DNA repair, DinP homolog; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.797 |
Cgl0616 | dnaE2 | cg0713 | cg0738 | Conserved hypothetical protein. | PUTATIVE DNA POLYMERASE III ALPHA CHAIN; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.933 |
Cgl0616 | lexA | cg0713 | cg2114 | Conserved hypothetical protein. | PUTATIVE LEXA REPRESSOR TRANSCRIPTION REGULATOR PROTEIN; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.521 |
Cgl0617 | Cgl0616 | cg0714 | cg0713 | Polymerase involved in DNA repair. | Conserved hypothetical protein. | 0.999 |
Cgl0617 | dnaE2 | cg0714 | cg0738 | Polymerase involved in DNA repair. | PUTATIVE DNA POLYMERASE III ALPHA CHAIN; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.959 |
Cgl0617 | dnaN | cg0714 | cg0004 | Polymerase involved in DNA repair. | DNA POLYMERASE III, BETA SUBUNIT; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.926 |
Cgl0617 | lexA | cg0714 | cg2114 | Polymerase involved in DNA repair. | PUTATIVE LEXA REPRESSOR TRANSCRIPTION REGULATOR PROTEIN; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.765 |
Cgl0617 | recA | cg0714 | cg2141 | Polymerase involved in DNA repair. | DNA RECOMBINATION/REPAIR; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.637 |
Cgl0639 | Cgl0640 | cg0739 | cg0740 | PUTATIVE INTEGRAL MEMBRANE PROTEIN. | Membrane protein. | 0.983 |
Cgl0639 | dnaE2 | cg0739 | cg0738 | PUTATIVE INTEGRAL MEMBRANE PROTEIN. | PUTATIVE DNA POLYMERASE III ALPHA CHAIN; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.799 |
Cgl0640 | Cgl0639 | cg0740 | cg0739 | Membrane protein. | PUTATIVE INTEGRAL MEMBRANE PROTEIN. | 0.983 |
Cgl0640 | dnaE2 | cg0740 | cg0738 | Membrane protein. | PUTATIVE DNA POLYMERASE III ALPHA CHAIN; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.796 |
Cgl2346 | dnaE2 | cg2576 | cg0738 | Putative DNA polymerase III delta subunit. | PUTATIVE DNA POLYMERASE III ALPHA CHAIN; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.908 |
Cgl2346 | dnaN | cg2576 | cg0004 | Putative DNA polymerase III delta subunit. | DNA POLYMERASE III, BETA SUBUNIT; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.987 |
Cgl2346 | dnaZX | cg2576 | cg0296 | Putative DNA polymerase III delta subunit. | DNA POLYMERASE III GAMMA AND TAU SUBUNITS; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.987 |
dinP | Cgl0616 | cg2355 | cg0713 | Nucleotidyltransferase/DNA polymerase involved in DNA repair, DinP homolog; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Conserved hypothetical protein. | 0.797 |
dinP | dnaE2 | cg2355 | cg0738 | Nucleotidyltransferase/DNA polymerase involved in DNA repair, DinP homolog; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | PUTATIVE DNA POLYMERASE III ALPHA CHAIN; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.973 |
dinP | dnaN | cg2355 | cg0004 | Nucleotidyltransferase/DNA polymerase involved in DNA repair, DinP homolog; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA POLYMERASE III, BETA SUBUNIT; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.922 |
dinP | lexA | cg2355 | cg2114 | Nucleotidyltransferase/DNA polymerase involved in DNA repair, DinP homolog; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | PUTATIVE LEXA REPRESSOR TRANSCRIPTION REGULATOR PROTEIN; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.956 |