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Cgl0721 Cgl0721 thyA thyA thyX thyX glyA glyA Cgl0722 Cgl0722 folC folC sigB sigB Cgl0107 Cgl0107 metF metF
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Predicted Interactions
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textmining
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Cgl0721Putative dihydrofolate reductase. (189 aa)    
Predicted Functional Partners:
thyA
PROBABLE THYMIDYLATE SYNTHASE; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.996
thyX
Similar to thymidylate synthase complementing protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
     
 0.983
glyA
Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.679
Cgl0722
Lactoylglutathione lyase or related lyase.
  
  
 0.625
folC
FOLYLPOLYGLUTAMATE SYNTHASE; Belongs to the folylpolyglutamate synthase family.
     
 0.549
sigB
RNA POLYMERASE SIGMA FACTOR; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.466
Cgl0107
Glyoxalase/Bleomycin resistance protein/Dioxygenas.
 
  
 0.418
metF
5,10-Methylenetetrahydrofolate Reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.412
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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