STRINGSTRING
sigH sigH sigB sigB rpoC rpoC rpoB rpoB cg0877 cg0877 sigD sigD trxB trxB rpoA rpoA pknB pknB mrx1 mrx1 rpoZ rpoZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
sigHPUTATIVE RNA POLYMERASE SIGMA FACTOR, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (206 aa)    
Predicted Functional Partners:
sigB
RNA POLYMERASE SIGMA FACTOR; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
  
 0.986
rpoC
DNA-DIRECTED RNA POLYMERASE BETA' CHAIN; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.983
rpoB
DNA-DIRECTED RNA POLYMERASE BETA CHAIN; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.979
cg0877
Putative anti-sigma factor.
  
 
 0.969
sigD
PUTATIVE RNA POLYMERASE SIGMA FACTOR, ECF family; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.937
trxB
THIOREDOXIN REDUCTASE.
  
  
 0.799
rpoA
DNA-DIRECTED RNA POLYMERASE ALPHA SUBUNIT; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.781
pknB
EUKARYOTIC-TYPE SERINE/THREONINE KINASE; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
  
 
 0.779
mrx1
Glutaredoxin or related protein; Involved in defense against toxic arsenate. Involved in the mycothiol/myoredoxin redox pathway which uses a mycothioltransferase mechanism; functions as a monothiol mixed disulfide reductase and is recycled by a second mycothiol forming mycothione which in turn is reduced in a NADPH-dependent manner.
   
  
 0.773
rpoZ
DNA-directed RNA polymerase subunit K/omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.763
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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