STRINGSTRING
betP betP proP proP mscL mscL kup kup mtrA mtrA mtrB mtrB Cgl1002 Cgl1002 putP putP Cgl2497 Cgl2497 metS metS Cgl2942 Cgl2942
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
betPGlycine betaine transporter; Involved in response to osmotic stress. High-affinity glycine betaine-specific uptake system, which couples the uptake of glycine betaine to the symport of two Na(+) ions. Transport is driven both by the Na(+) gradient and by the electrical potential. In addition, functions both as an osmosensor and as an osmoregulator that transduces signal to the catalytic part of the carrier protein, which adapts its activity to the extent of osmotic stress. (595 aa)    
Predicted Functional Partners:
proP
PROLINE/ECTOINE CARRIER; Involved in the uptake of osmoprotectants. Can transport ectoine and proline. Protons are probably the coupling ions.
   
  
 0.982
mscL
LARGE CONDUCTANCE MECHANOSENSITIVE CHANNEL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
  
  
 0.981
kup
K+ potassium transporter; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
   
  
 0.945
mtrA
Response regulator.
      
 0.919
mtrB
Signal transduction histidine kinase.
   
  
 0.774
Cgl1002
Allophanate hydrolase subunit 2.
      
 0.685
putP
PROLINE TRANSPORT SYSTEM; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.645
Cgl2497
SECRETED PEPTIDASE, M23/M37 FAMILY.
      
 0.637
metS
METHIONYL-TRNA SYNTHETASE; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
    0.626
Cgl2942
Putative membrane protein.
   
  
 0.626
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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