STRINGSTRING
ksgA ksgA ispE ispE rpf2 rpf2 Cgl0912 Cgl0912 Cgl0908 Cgl0908 ychF ychF pdxK pdxK gidB gidB rpsL rpsL rpsD rpsD rpsI rpsI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
ksgAPUTATIVE DIMETHYLADENOSINE TRANSFERASE; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (293 aa)    
Predicted Functional Partners:
ispE
PUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
 0.998
rpf2
Putative RPF2 precursor, secreted protein; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity).
  
  
 0.966
Cgl0912
ATPase component of ABC transporters with duplicated ATPase domains.
  
  
 0.950
Cgl0908
TatD related DNase.
 
  
 0.933
ychF
Predicted GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.927
pdxK
PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family.
  
  
 0.882
gidB
GLUCOSE-INHIBITED DIVISION PROTEIN, GIDB(S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE); Specifically methylates the N7 position of guanine in position 518 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.880
rpsL
RIBOSOMAL PROTEIN S12; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.867
rpsD
RIBOSOMAL PROTEIN S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.840
rpsI
30S RIBOSOMAL PROTEIN S9; Belongs to the universal ribosomal protein uS9 family.
 
 
 0.831
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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