STRINGSTRING
argH argH argG argG argF argF argC argC argB argB argJ argJ argD argD argR argR purB purB aspA aspA mdh mdh
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
argHARGININOSUCCINATE LYASE. (477 aa)    
Predicted Functional Partners:
argG
ARGININOSUCCINATE SYNTHASE; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 0.999
argF
ORNITHINE CARBAMOYLTRANSFERASE; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 0.991
argC
N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.987
argB
ACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.986
argJ
GLUTAMATE N-ACETYLTRANSFERASE; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
  
 0.985
argD
ACETYLORNITHINE AMINOTRANSFERASE; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.979
argR
ARGININE REPRESSOR; Regulates arginine biosynthesis genes.
  
  
 0.973
purB
ADENYLOSUCCINATE LYASE; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.914
aspA
ASPARTATE AMMONIA-LYASE (ASPARTASE).
     
 0.907
mdh
MALATE DEHYDROGENASE OXIDOREDUCTASE PROTEIN; Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits higher catalytic efficiency for oxaloacetate reduction than for malate oxidation in vitro. Almost equally active both for NADH and NADPH on the bases of the kcat values at pH 6.5, but catalytic efficiency for oxaloacetate reduction is 50-fold higher with NADH.
   
 0.830
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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