node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl0778 | cobB | cg0888 | cg0745 | NTP pyrophosphohydrolase. | Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.917 |
Cgl0778 | nadD | cg0888 | cg2584 | NTP pyrophosphohydrolase. | PUTATIVE NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.905 |
Cgl0778 | nadE | cg0888 | cg2792 | NTP pyrophosphohydrolase. | NAD-SYNTHETASE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.903 |
Cgl0778 | ppnK | cg0888 | cg1601 | NTP pyrophosphohydrolase. | POLY(P)/ATP-NAD KINASE; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.901 |
Cgl1410 | Cgl1412 | cg1598 | cg1600 | Sugar phosphatase of the HAD superfamily. | Predicted rRNA methylase. | 0.761 |
Cgl1410 | ppnK | cg1598 | cg1601 | Sugar phosphatase of the HAD superfamily. | POLY(P)/ATP-NAD KINASE; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.842 |
Cgl1410 | recN | cg1598 | cg1602 | Sugar phosphatase of the HAD superfamily. | DNA REPAIR PROTEIN RECN; May be involved in recombinational repair of damaged DNA. | 0.837 |
Cgl1412 | Cgl1410 | cg1600 | cg1598 | Predicted rRNA methylase. | Sugar phosphatase of the HAD superfamily. | 0.761 |
Cgl1412 | ppnK | cg1600 | cg1601 | Predicted rRNA methylase. | POLY(P)/ATP-NAD KINASE; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.953 |
Cgl1412 | recN | cg1600 | cg1602 | Predicted rRNA methylase. | DNA REPAIR PROTEIN RECN; May be involved in recombinational repair of damaged DNA. | 0.731 |
cobB | Cgl0778 | cg0745 | cg0888 | Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | NTP pyrophosphohydrolase. | 0.917 |
cobB | nadD | cg0745 | cg2584 | Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | PUTATIVE NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.941 |
cobB | nadE | cg0745 | cg2792 | Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | NAD-SYNTHETASE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.941 |
cobB | ppnK | cg0745 | cg1601 | Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | POLY(P)/ATP-NAD KINASE; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.922 |
gnd | pgi | cg1643 | cg0973 | 6-PHOSPHOGLUCONATE DEHYDROGENASE; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | GLUCOSE-6-PHOSPHATE ISOMERASE. | 0.868 |
gnd | ppnK | cg1643 | cg1601 | 6-PHOSPHOGLUCONATE DEHYDROGENASE; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | POLY(P)/ATP-NAD KINASE; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.770 |
gnd | zwf | cg1643 | cg1778 | 6-PHOSPHOGLUCONATE DEHYDROGENASE; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.999 |
nadD | Cgl0778 | cg2584 | cg0888 | PUTATIVE NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NTP pyrophosphohydrolase. | 0.905 |
nadD | cobB | cg2584 | cg0745 | PUTATIVE NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.941 |
nadD | nadE | cg2584 | cg2792 | PUTATIVE NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD-SYNTHETASE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.993 |