node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fmu | metK | cg1802 | cg1806 | PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.679 |
fmu | ribA | cg1802 | cg1798 | PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | PUTATIVE GTP CYCLOHYDROLASE II/3,4-DIHYDROXY-2-BUTANONE-4-PHOSPHATESYNTHASE; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.937 |
fmu | ribC | cg1802 | cg1799 | PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | PUTATIVE RIBOFLAVIN SYNTHASE. | 0.815 |
fmu | ribF | cg1802 | cg2169 | PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | PUTATIVE RIBOFLAVIN KINASE; Belongs to the ribF family. | 0.701 |
fmu | ribG | cg1802 | cg1800 | PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | PUTATIVE BIFUNCTIONAL RIBOFLAVIN-SPECIFIC DEAMINASE/REDUCTASE; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.944 |
fmu | ribH | cg1802 | cg1797 | PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | RIBOFLAVIN SYNTHASE, BETA CHAIN; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.948 |
fmu | rpe | cg1802 | cg1801 | PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | RIBULOSE-5-PHOSPHATE-3-EPIMERASE; Belongs to the ribulose-phosphate 3-epimerase family. | 0.948 |
metK | fmu | cg1806 | cg1802 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.679 |
metK | mscL | cg1806 | cg1001 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | LARGE CONDUCTANCE MECHANOSENSITIVE CHANNEL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.892 |
metK | pyrB | cg1806 | cg1816 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.549 |
metK | ribA | cg1806 | cg1798 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | PUTATIVE GTP CYCLOHYDROLASE II/3,4-DIHYDROXY-2-BUTANONE-4-PHOSPHATESYNTHASE; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.727 |
metK | ribC | cg1806 | cg1799 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | PUTATIVE RIBOFLAVIN SYNTHASE. | 0.759 |
metK | ribF | cg1806 | cg2169 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | PUTATIVE RIBOFLAVIN KINASE; Belongs to the ribF family. | 0.468 |
metK | ribG | cg1806 | cg1800 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | PUTATIVE BIFUNCTIONAL RIBOFLAVIN-SPECIFIC DEAMINASE/REDUCTASE; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.750 |
metK | ribH | cg1806 | cg1797 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | RIBOFLAVIN SYNTHASE, BETA CHAIN; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.956 |
metK | rpe | cg1806 | cg1801 | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | RIBULOSE-5-PHOSPHATE-3-EPIMERASE; Belongs to the ribulose-phosphate 3-epimerase family. | 0.875 |
mscL | metK | cg1001 | cg1806 | LARGE CONDUCTANCE MECHANOSENSITIVE CHANNEL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.892 |
mscL | ribH | cg1001 | cg1797 | LARGE CONDUCTANCE MECHANOSENSITIVE CHANNEL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | RIBOFLAVIN SYNTHASE, BETA CHAIN; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.899 |
pyrB | metK | cg1816 | cg1806 | ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.549 |
pyrB | ribA | cg1816 | cg1798 | ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | PUTATIVE GTP CYCLOHYDROLASE II/3,4-DIHYDROXY-2-BUTANONE-4-PHOSPHATESYNTHASE; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.549 |