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ribH ribH ribA ribA ribC ribC ribG ribG ribF ribF ribD ribD metK metK fmu fmu mscL mscL pyrB pyrB rpe rpe
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ribHRIBOFLAVIN SYNTHASE, BETA CHAIN; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (159 aa)    
Predicted Functional Partners:
ribA
PUTATIVE GTP CYCLOHYDROLASE II/3,4-DIHYDROXY-2-BUTANONE-4-PHOSPHATESYNTHASE; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
 
 
 0.999
ribC
PUTATIVE RIBOFLAVIN SYNTHASE.
 
 0.999
ribG
PUTATIVE BIFUNCTIONAL RIBOFLAVIN-SPECIFIC DEAMINASE/REDUCTASE; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
 0.999
ribF
PUTATIVE RIBOFLAVIN KINASE; Belongs to the ribF family.
  
  
 0.995
ribD
RIBOFLAVIN SPECIFIC DEAMINASE.
  
 
 0.966
metK
S-Adenosylmethionine Synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.956
fmu
PUTATIVE 16S RRNA M(5)C 967 METHYLTRANSFERASE; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.948
mscL
LARGE CONDUCTANCE MECHANOSENSITIVE CHANNEL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
  
  
 0.899
pyrB
ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
    0.897
rpe
RIBULOSE-5-PHOSPHATE-3-EPIMERASE; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.849
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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