STRINGSTRING
rnhB rnhB Cgl2119 Cgl2119 Cgl1177 Cgl1177 lepB lepB thrS thrS Cgl2032 Cgl2032 dnaN dnaN Cgl1313 Cgl1313 Cgl2236 Cgl2236 rel rel polA polA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhBPROBABLE RIBONUCLEASE HII PROTEIN; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (222 aa)    
Predicted Functional Partners:
Cgl2119
Conserved hypothetical protein.
  
  
 0.982
Cgl1177
SIMILAR TO GTP PYROPHOSPHOKINASE.
     
 0.961
lepB
PROBABLE SIGNAL PEPTIDASE I (SPASE I); Belongs to the peptidase S26 family.
  
  
 0.939
thrS
THREONYL-TRNA SYNTHETASE; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
  
 0.842
Cgl2032
Putative CTP synthase (UTP-ammonia lyase).
  
    0.836
dnaN
DNA POLYMERASE III, BETA SUBUNIT; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.827
Cgl1313
Putative metal dependent phosphohydrolase, relA/spoT homolog.
  
  
 0.816
Cgl2236
Ribonuclease HI.
  
 
 0.810
rel
PPGPP SYNTHETASE, PPGPP PYROPHOSPHORYLASE; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp. It also has (p)ppGpp-degrading activities.
 
  
 0.793
polA
DNA POLYMERASE I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.790
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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