node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ftsI | ftsK | cg2375 | cg2158 | PENICILLIN-BINDING PROTEIN 2X. | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | 0.945 |
ftsI | ftsQ | cg2375 | cg2367 | PENICILLIN-BINDING PROTEIN 2X. | Cell division septal protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.999 |
ftsI | ftsW | cg2375 | cg2370 | PENICILLIN-BINDING PROTEIN 2X. | Bacterial cell division membrane protein; Belongs to the SEDS family. | 0.999 |
ftsI | ftsZ | cg2375 | cg2366 | PENICILLIN-BINDING PROTEIN 2X. | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.995 |
ftsI | murC | cg2375 | cg2368 | PENICILLIN-BINDING PROTEIN 2X. | PROBABLE UDP-N-ACETYLMURAMATE--ALANINE LIGASE PROTEIN; Cell wall formation; Belongs to the MurCDEF family. | 0.967 |
ftsI | murD | cg2375 | cg2371 | PENICILLIN-BINDING PROTEIN 2X. | UDP-N-ACETYLMURAMOYLALANINE D-GLUTAMATE LIGASE. | 0.959 |
ftsI | murF | cg2375 | cg2373 | PENICILLIN-BINDING PROTEIN 2X. | D-ALANINE:D-ALANINE-ADDING ENZYME; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.956 |
ftsI | murG | cg2375 | cg2369 | PENICILLIN-BINDING PROTEIN 2X. | Peptidoglycan biosynthesis protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.974 |
ftsI | pbpA | cg2375 | cg0060 | PENICILLIN-BINDING PROTEIN 2X. | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE. | 0.950 |
ftsI | sepF | cg2375 | cg2363 | PENICILLIN-BINDING PROTEIN 2X. | Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.854 |
ftsK | ftsI | cg2158 | cg2375 | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | PENICILLIN-BINDING PROTEIN 2X. | 0.945 |
ftsK | ftsQ | cg2158 | cg2367 | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Cell division septal protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.984 |
ftsK | ftsW | cg2158 | cg2370 | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Bacterial cell division membrane protein; Belongs to the SEDS family. | 0.932 |
ftsK | ftsZ | cg2158 | cg2366 | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.992 |
ftsK | murC | cg2158 | cg2368 | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | PROBABLE UDP-N-ACETYLMURAMATE--ALANINE LIGASE PROTEIN; Cell wall formation; Belongs to the MurCDEF family. | 0.422 |
ftsK | murG | cg2158 | cg2369 | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Peptidoglycan biosynthesis protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.536 |
ftsK | sepF | cg2158 | cg2363 | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.724 |
ftsQ | ftsI | cg2367 | cg2375 | Cell division septal protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | PENICILLIN-BINDING PROTEIN 2X. | 0.999 |
ftsQ | ftsK | cg2367 | cg2158 | Cell division septal protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | 0.984 |
ftsQ | ftsW | cg2367 | cg2370 | Cell division septal protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | Bacterial cell division membrane protein; Belongs to the SEDS family. | 0.999 |