STRINGSTRING
lipB lipB lipA lipA lplA lplA sucB sucB fas-IB fas-IB fas-IA fas-IA pks pks pdxS pdxS acpM acpM Maf Maf Cgl2210 Cgl2210
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
lipBLIPOATE-PROTEIN LIGASE B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (251 aa)    
Predicted Functional Partners:
lipA
LIPOIC ACID SYNTHASE; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.999
lplA
LIPOATE-PROTEIN LIGASE.
  
 0.969
sucB
DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE; Is essential for both 2-oxoglutarate dehydrogenase (ODH) and pyruvate dehydrogenase (PDH) activities, but AceF has exclusively transacetylase (and no transsuccinylase) activity. The lipoyl residues required for ODH activity are likely provided by AceF. Belongs to the 2-oxoacid dehydrogenase family.
 
 
 0.877
fas-IB
FATTY ACID SYNTHASE.
    
 0.837
fas-IA
FATTY ACID SYNTHASE.
   
 0.837
pks
POLYKETIDE SYNTHASE.
  
 0.784
pdxS
Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
      
 0.770
acpM
ACYL CARRIER PROTEIN (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 0.744
Maf
Nucleotide-binding protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
   
  
 0.581
Cgl2210
Putative membrane protein.
       0.530
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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