node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
amtB | glnA | cg2261 | cg2429 | LOW AFFINITY AMMONIUM UPTAKE PROTEIN. | GLUTAMINE SYNTHETASE I. | 0.989 |
amtB | glnD | cg2261 | cg2258 | LOW AFFINITY AMMONIUM UPTAKE PROTEIN. | PROBABLE PROTEIN-PII URIDYLYLTRANSFERASE; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism (By simil [...] | 0.996 |
amtB | glnE | cg2261 | cg2446 | LOW AFFINITY AMMONIUM UPTAKE PROTEIN. | GLUTAMATE-AMMONIA-LIGASE ADENYLYLTRANSFERASE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.751 |
amtB | glnK | cg2261 | cg2260 | LOW AFFINITY AMMONIUM UPTAKE PROTEIN. | Nitrogen regulatory protein PII; Belongs to the P(II) protein family. | 0.999 |
amtB | gltB | cg2261 | cg0229 | LOW AFFINITY AMMONIUM UPTAKE PROTEIN. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | 0.853 |
amtB | gltD | cg2261 | cg0230 | LOW AFFINITY AMMONIUM UPTAKE PROTEIN. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE. | 0.714 |
gdh | glnA | cg2280 | cg2429 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE SYNTHETASE I. | 0.959 |
gdh | glsK | cg2280 | cg2728 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | PUTATIVE GLUTAMINASE; Belongs to the glutaminase family. | 0.911 |
gdh | gltB | cg2280 | cg0229 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | 0.999 |
gdh | gltD | cg2280 | cg0230 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE. | 0.939 |
gdh | putA | cg2280 | cg0129 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | PROLINE DEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE. | 0.954 |
glmS | glnA | cg2492 | cg2429 | PROBABLE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GLUTAMINE SYNTHETASE I. | 0.926 |
glmS | glsK | cg2492 | cg2728 | PROBABLE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | PUTATIVE GLUTAMINASE; Belongs to the glutaminase family. | 0.951 |
glmS | gltB | cg2492 | cg0229 | PROBABLE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | 0.971 |
glmS | gltD | cg2492 | cg0230 | PROBABLE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE. | 0.913 |
glnA | amtB | cg2429 | cg2261 | GLUTAMINE SYNTHETASE I. | LOW AFFINITY AMMONIUM UPTAKE PROTEIN. | 0.989 |
glnA | gdh | cg2429 | cg2280 | GLUTAMINE SYNTHETASE I. | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.959 |
glnA | glmS | cg2429 | cg2492 | GLUTAMINE SYNTHETASE I. | PROBABLE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.926 |
glnA | glnD | cg2429 | cg2258 | GLUTAMINE SYNTHETASE I. | PROBABLE PROTEIN-PII URIDYLYLTRANSFERASE; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism (By simil [...] | 0.984 |
glnA | glnE | cg2429 | cg2446 | GLUTAMINE SYNTHETASE I. | GLUTAMATE-AMMONIA-LIGASE ADENYLYLTRANSFERASE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.955 |