node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl2286 | Cgl2289 | cg2511 | cg2514 | Putative membrane protein containing CBS domain. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.722 |
Cgl2286 | bex | cg2511 | cg2510 | Putative membrane protein containing CBS domain. | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.847 |
Cgl2286 | dnaJ2 | cg2511 | cg2515 | Putative membrane protein containing CBS domain. | Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...] | 0.771 |
Cgl2286 | hemN | cg2511 | cg2517 | Putative membrane protein containing CBS domain. | PUTATIVE ANAEROBIC COPROPORPHYRINOGEN III OXIDASE; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.600 |
Cgl2286 | hrcA | cg2511 | cg2516 | Putative membrane protein containing CBS domain. | Transcriptional regulator of heat shock genes; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.624 |
Cgl2286 | phoH2 | cg2511 | cg2513 | Putative membrane protein containing CBS domain. | Phosphate starvation-inducible protein. | 0.855 |
Cgl2286 | recO | cg2511 | cg2509 | Putative membrane protein containing CBS domain. | Recombinational DNA repair protein (RecF pathway); Involved in DNA repair and RecF pathway recombination. | 0.771 |
Cgl2286 | uppS2 | cg2511 | cg2508 | Putative membrane protein containing CBS domain. | PUTATIVE UNDECAPRENYL DIPHOSPHATE SYNTHASE; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.609 |
Cgl2286 | ybeY | cg2511 | cg2512 | Putative membrane protein containing CBS domain. | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.899 |
Cgl2289 | Cgl2286 | cg2514 | cg2511 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Putative membrane protein containing CBS domain. | 0.722 |
Cgl2289 | bex | cg2514 | cg2510 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.688 |
Cgl2289 | dnaJ2 | cg2514 | cg2515 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...] | 0.897 |
Cgl2289 | hemN | cg2514 | cg2517 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | PUTATIVE ANAEROBIC COPROPORPHYRINOGEN III OXIDASE; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.674 |
Cgl2289 | hrcA | cg2514 | cg2516 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Transcriptional regulator of heat shock genes; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.877 |
Cgl2289 | phoH2 | cg2514 | cg2513 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Phosphate starvation-inducible protein. | 0.726 |
Cgl2289 | recO | cg2514 | cg2509 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Recombinational DNA repair protein (RecF pathway); Involved in DNA repair and RecF pathway recombination. | 0.668 |
Cgl2289 | uppS2 | cg2514 | cg2508 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | PUTATIVE UNDECAPRENYL DIPHOSPHATE SYNTHASE; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.577 |
Cgl2289 | ybeY | cg2514 | cg2512 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.725 |
bex | Cgl2286 | cg2510 | cg2511 | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Putative membrane protein containing CBS domain. | 0.847 |
bex | Cgl2289 | cg2510 | cg2514 | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.688 |