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Cgl2289 Cgl2289 Cgl2603 Cgl2603 Cgl3053 Cgl3053 dnaJ2 dnaJ2 hrcA hrcA Cgl1959 Cgl1959 sahH sahH phoH2 phoH2 ybeY ybeY Cgl2286 Cgl2286 Cgl1960 Cgl1960
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cgl2289Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (241 aa)    
Predicted Functional Partners:
Cgl2603
Dipeptide/tripeptide permease.
     
 0.981
Cgl3053
Dipeptide/tripeptide permease.
     
 0.981
dnaJ2
Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...]
  
   0.897
hrcA
Transcriptional regulator of heat shock genes; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
 
  
 0.877
Cgl1959
ABC TRANSPORTER, ATP-BINDING PROTEIN.
  
  
 0.807
sahH
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
  
 0.771
phoH2
Phosphate starvation-inducible protein.
  
    0.726
ybeY
Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
    0.725
Cgl2286
Putative membrane protein containing CBS domain.
  
    0.722
Cgl1960
PREDICTED PERMEASE (COBALT PERMEASE SUBFAMILY).
      
 0.700
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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