STRINGSTRING
nadD nadD nadE nadE nadC nadC Cgl2517 Cgl2517 ppnK ppnK cobB cobB Cgl1963 Cgl1963 Cgl0778 Cgl0778 Cgl0328 Cgl0328 nadA nadA rsfS rsfS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDPUTATIVE NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (226 aa)    
Predicted Functional Partners:
nadE
NAD-SYNTHETASE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
 
 0.993
nadC
PUTATIVE NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE; Belongs to the NadC/ModD family.
    
 0.985
Cgl2517
Nicotinic acid phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 0.974
ppnK
POLY(P)/ATP-NAD KINASE; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
 
 0.945
cobB
Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily.
   
 0.941
Cgl1963
Similar to competence-and mitomycin-induced protein; Belongs to the CinA family.
  
 
 0.929
Cgl0778
NTP pyrophosphohydrolase.
   
 
 0.905
Cgl0328
PROBABLE 5'-NUCLEOTIDASE PRECURSOR; Belongs to the 5'-nucleotidase family.
     
  0.900
nadA
QUINOLINATE SYNTHETASE; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
     
 0.870
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.860
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.