STRINGSTRING
Cgl2377 Cgl2377 Cgl1991 Cgl1991 gntP gntP sdhCD sdhCD prpD2 prpD2 prpC2 prpC2 Cgl2887 Cgl2887 Cgl1992 Cgl1992 prpB2 prpB2 Cgl1993 Cgl1993 folC folC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cgl2377ABC-type dipeptide/oligopeptide/nickel transport system, secreted component. (525 aa)    
Predicted Functional Partners:
Cgl1991
ABC-type peptide transport system, permease component.
 
  
 0.909
gntP
GLUCONATE PERMEASE.
   
    0.858
sdhCD
Succinate dehydrogenase CD.
   
    0.853
prpD2
PROPIONATE CATABOLISM PROTEIN PRPD; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield the cis isomer 2-methyl-aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate (By similarity); Belongs to the PrpD family.
   
    0.853
prpC2
METHYLCITRATE SYNTHASE; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity.
   
    0.853
Cgl2887
Flavin-containing monooxygenase (FMO).
   
    0.853
Cgl1992
ABC-type peptide transport system, permease component.
 
  
 0.847
prpB2
PROBABLE METHYLISOCITRIC ACID LYASE; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2- methylisocitrate to yield pyruvate and succinate via an alpha-carboxy- carbanion intermediate; Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
   
    0.726
Cgl1993
ATPase component of peptide ABC-type transport system, contains duplicated ATPase domains; Belongs to the ABC transporter superfamily.
 
  
 0.644
folC
FOLYLPOLYGLUTAMATE SYNTHASE; Belongs to the folylpolyglutamate synthase family.
       0.624
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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