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pncA pncA Cgl2517 Cgl2517 gntV gntV cobB cobB iunH3 iunH3 iunH2 iunH2 iunH1 iunH1 nadD nadD nadC nadC nadA nadA rpsL rpsL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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[Homology]
Score
pncANICOTINAMIDASE/ PYRAZINAMIDASE. (186 aa)    
Predicted Functional Partners:
Cgl2517
Nicotinic acid phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 0.998
gntV
PUTATIVE GLUCONOKINASE.
 
    0.929
cobB
Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily.
  
 0.917
iunH3
INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE.
     
 0.904
iunH2
PUTATIVE NUCLEOSIDE HYDROLASE PROTEIN.
     
 0.904
iunH1
INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE.
     
 0.904
nadD
PUTATIVE NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.821
nadC
PUTATIVE NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE; Belongs to the NadC/ModD family.
  
 
 0.816
nadA
QUINOLINATE SYNTHETASE; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
      
 0.761
rpsL
RIBOSOMAL PROTEIN S12; With S4 and S5 plays an important role in translational accuracy.
  
  
 0.759
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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