STRINGSTRING
pgm pgm pgi pgi glgP2 glgP2 glgP1 glgP1 malQ malQ Cgl2647 Cgl2647 glgC glgC glgA glgA glgB glgB glk glk tkt tkt
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
pgmPHOSPHOGLUCOMUTASE. (554 aa)    
Predicted Functional Partners:
pgi
GLUCOSE-6-PHOSPHATE ISOMERASE.
  
 0.993
glgP2
ALPHA-GLUCAN PHOSPHORYLASE, GLYCOGEN PHOSPHORYLASE.
  
 
 0.983
glgP1
PUTATIVE GLYCOGEN PHOSPHORYLASE; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.978
malQ
4-ALPHA-GLUCANOTRANSFERASE.
  
 
 0.974
Cgl2647
Transcriptional regulator ROK family, putative sugar kinase.
     
 0.961
glgC
ADP-GLUCOSE PYROPHOSPHORYLASE; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
    
 0.959
glgA
GLYCOSYL TRANSFERASE.
  
 0.950
glgB
1,4-ALPHA-GLUCAN BRANCHING ENZYME; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
  
 0.947
glk
GLUCOKINASE, TRANSCRIPTIONAL REGULATOR.
   
 
 0.947
tkt
TRANSKETOLASE; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.944
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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