STRINGSTRING
cysE cysE cysK cysK cysS cysS aecD aecD sdaA sdaA glyA glyA serB serB cysS2 cysS2 hom hom thrB thrB tdcB tdcB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysESerine O-Acetyltransferase. (188 aa)    
Predicted Functional Partners:
cysK
O-Acetylserine (Thiol)-Lyase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.999
cysS
CYSTEINE TRNA SYNTHETASE; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.971
aecD
Cystathionine beta-Lyase.
      
 0.963
sdaA
PROBABLE L-SERINE DEHYDRATASE (L-SERINE DEAMINASE); Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.911
glyA
Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.894
serB
Phosphoserine Phosphatase.
  
 
 0.869
cysS2
PUTATIVE CYSTEINE TRNA SYNTHETASE; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
  
 0.867
hom
Homoserine Dehydrogenase; Belongs to the homoserine dehydrogenase family.
   
 
 0.839
thrB
Homoserine Kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
   
 
 0.832
tdcB
THREONINE DEHYDRATASE.
  
 
 0.822
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
Server load: low (14%) [HD]