STRINGSTRING
disA disA radA radA Cgl2664 Cgl2664 Cgl1983 Cgl1983 Cgl2349 Cgl2349 Cgl2661 Cgl2661 ispD ispD Cgl1325 Cgl1325 Cgl0775 Cgl0775 Cgl0776 Cgl0776 ispF ispF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
disAPredicted nucleic-acid-binding protein (contains the HHH domain); Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. (366 aa)    
Predicted Functional Partners:
radA
PROBABLE ATP-DEPENDENT PROTEASE, DNA REPAIR (ATP-B; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.973
Cgl2664
Putative secreted protein.
  
  
 0.657
Cgl1983
Exopolyphosphatase-related protein.
  
  
 0.646
Cgl2349
Protein DegV family; Binds long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
  
    0.631
Cgl2661
CarD-like transcriptional regulator.
 
     0.601
ispD
2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANS; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
  
    0.578
Cgl1325
Predicted kinase related to dihydroxyacetone kinase.
  
     0.562
Cgl0775
HELICASE, UVRD/REP FAMILY; Belongs to the helicase family. UvrD subfamily.
   
    0.494
Cgl0776
PROBABLE DNA HELICASE II PROTEIN; Belongs to the helicase family. UvrD subfamily.
   
    0.482
ispF
2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
  
    0.454
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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