STRINGSTRING
pknG pknG odhI odhI Cgl2749 Cgl2749 Cgl2750 Cgl2750 ppp ppp pknB pknB odhA odhA Cgl0046 Cgl0046 pknE pknE Cgl0047 Cgl0047 ftsZ ftsZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pknGSerine/threonine protein kinase. (822 aa)    
Predicted Functional Partners:
odhI
PUTATIVE SIGNAL TRANSDUCTION PROTEIN, FHA DOMAIN; An essential component of the PknG signaling pathway. When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase.
 
 
 0.999
Cgl2749
Putative membrane protein.
 
  
 0.985
Cgl2750
ABC-type amino acid transport system, secreted component.
 
  
 0.983
ppp
PROTEIN PHOSPHATASE.
 
 
 0.930
pknB
EUKARYOTIC-TYPE SERINE/THREONINE KINASE; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
 
 
0.826
odhA
2-OXOGLUTARATE DEHYDROGENASE; Catalyzes the E1 and E2 reactions as part of 2-oxoglutarate dehydrogenase (ODH) activity, to convert 2-oxoglutarate to succinyl-CoA and CO(2). OdhA has reductase activity with 2-oxoglutarate but does not react with pyruvate, and also displays transsuccinylase but no transacetylase activity. Since OdhA is not lipoylated, the succinyltransferase activity of its E2 domain is dependent on lipoyl residues of the acetyltransferase AceF.
   
  
 0.805
Cgl0046
Secreted PROTEIN.
 
 
 
 0.803
pknE
Putative secreted protein.
   
  
 0.795
Cgl0047
Conserved hypothetical protein.
 
 
 0.753
ftsZ
Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
  
 0.726
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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