STRINGSTRING
tpbB tpbB rocR rocR yfiR yfiR yfiB yfiB PA3825 PA3825 arr arr PA2133 PA2133 tpbA tpbA PA2567 PA2567 PA4781 PA4781 fimX fimX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpbBDiguanylate cyclase TpbB; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (435 aa)    
Predicted Functional Partners:
rocR
RocR; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 0.995
yfiR
YfiR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.990
yfiB
YfiB; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.984
PA3825
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
 0.928
arr
Aminoglycoside response regulator; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 0.917
PA2133
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.908
tpbA
Protein tyrosine phosphatase TpbA; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
      
 0.884
PA2567
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 0.847
PA4781
Cyclic di-GMP phosphodiesterase; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP. Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP. Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture. May act preferentially as a pGpG binding protein.
 
  
 0.832
fimX
FimX; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.830
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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