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fpvA2 fpvA2 fecR fecR azo2512 azo2512 azo1311 azo1311 azo2996 azo2996 azo2513 azo2513 fecI fecI azo0235 azo0235 tolA tolA tonB1 tonB1 azo0708 azo0708
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fpvA2Iron-regulated outer membrane protein. TonB-dependent receptor protein. Homolog to fpvA, a ferripyoverdine receptor precursor in P. aeruginosa. Similar to PupA protein of P. putida WCS,this protein is a receptor for the iron-bound form of pesudobactin, a compound structurally very; High confidence in function and specificity. (737 aa)    
Predicted Functional Partners:
fecR
Putative transmembrane sensor; FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm. Involved in iron metabolism; High confidence in function and specificity.
 
 
 0.936
azo2512
Probable FecR-like transmembrane sensor involved in iron metabolism. FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm; High confidence in function and specificity.
 
 
 0.935
azo1311
Conserved hypothetical protein Has 2 PF05488 PAAR motif(IPR008727);This motif is found usually in pairs in a family of bacterial membrane proteins. It is also found as a triplet of tandem repeats comprising the entire length in a another family of hypothetical proteins; Function unclear.
    
   0.744
azo2996
Conserved hypothetical membrane protein. Homology to PA2403 of Pseudomonas aeruginosa of 38% (trembl|Q8G8F6). Has 3 copies of PF03929, PepSY-associated TM helix;IPR005625 pEPsy_tm; This domain represents a conserved TM helix found in bacterial proteins. Has PF03413, Peptidase propeptide and YPEB domain; IPR005075,Propep_PepSY:This region is likely to have an protease inhibitory function (personal obs:C Yeats). This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to no [...]
 
  
 0.740
azo2513
Putative sigma factor, ECF subfamily; Probable fecI-like RNA polymerase sigma factor. THE SIGMA FACTOR IS AN INITIATION FACTOR THAT PROMOTES ATTACHMENT OF THE RNA POLYMERASE TO SPECIFIC INITIATION SITES AND THEN IS RELEASED. THIS SIGMA FACTOR REGULATES THE FEC GENES FOR IRON DICITRATE TRANSPORT (PROBABLE). InterPro: Sigma factor ECF subfamily; Specificity unclear.
 
  
 0.654
fecI
Putative sigma-70 factor, ECF subfamily; FecI: belongs to the extracytoplasmic-function (ECF) sigma factor, which represent a subgroup of the sigma 70 family. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Involved in iron metabolism; High confidence in function and specificity.
 
  
 0.633
azo0235
Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi|47575633|ref|ZP_00245668.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein.
  
 
 0.587
tolA
Conserved hypothetical membrane protein. Homology to tolA of N. europaea of 39% (trembl|Q82XP0). no domains predicted InterPro: Proline-rich region (IPR000694) no signal peptide 1 TMHs; Conserved hypothetical protein.
  
 
 0.587
tonB1
Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear.
  
 
 0.587
azo0708
Conserved hypothetical secreted protein. Homology to ne1626 of N. europaea of 46% (trembl|Q82U75) no domains predicted signal peptide TMH in signal peptide; Conserved hypothetical protein.
  
 
 0.587
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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