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There are several matches for 'fructose-1,6-bisphosphatase'.
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6328 matches
showing page 1 of 317
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organism
protein
1)
Homo sapiens
TIGAR -
Fructose
-2,
6
-
bisphosphatase
TIGAR;
Fructose
-
bisphosphatase
hydrolyzing
fructose
-2,
6
-bisphosphate as well as
fructose
-1
,
6
-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of
fructose
-2,
6
-bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell death. Plays a [...]
[a.k.a. TIGAR-204, OTTHUMG00000168124, 3DCY]
2)
Homo sapiens
FBP1 -
Fructose
-1
,
6
-
bisphosphatase
1; Catalyzes the hydrolysis of
fructose
1,
6
-bisphosphate to
fructose
6
-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism [...]
[a.k.a. 5LDZ, U47918, ENST00000375326]
3)
Homo sapiens
FBP2 -
Fructose
-1
,
6
-
bisphosphatase
isozyme 2; Catalyzes the hydrolysis of
fructose
1,
6
-bisphosphate to
fructose
6
-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
[a.k.a. NP_003828.2, ENSP00000253269, 5L0A]
4)
Mus musculus
Tigar -
Fructose
-2,
6
-
bisphosphatase
TIGAR;
Fructose
-
bisphosphatase
hydrolyzing
fructose
-2,
6
-bisphosphate as well as
fructose
-1
,
6
-bisphosphate (By similarity). Acts as a negative regulator of glycolysis by lowering intracellular levels of
fructose
-2,
6
-bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell [...]
[a.k.a. ENSMUST00000039913, 319801, AA793651]
5)
Mus musculus
Fbp1 -
Fructose
-1
,
6
-
bisphosphatase
1; Catalyzes the hydrolysis of
fructose
1,
6
-bisphosphate to
fructose
6
-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism [...]
[a.k.a. BAE28940.1, Fructose bisphosphatase 1, CAA71946.1]
6)
Mus musculus
Fbp2 -
Fructose
-1
,
6
-
bisphosphatase
isozyme 2; Catalyzes the hydrolysis of
fructose
1,
6
-bisphosphate to
fructose
6
-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
[a.k.a. ENSMUST00000222000, BAE39101.1, Fbp-1]
7)
Drosophila melanogaster
fbp -
Fructose
-1
,
6
-
bisphosphatase
, isoform F;
Fructose
1,
6
-bisphosphate 1-phosphatase activity. It is involved in the biological process described with: gluconeogenesis;
fructose
6
-phosphate metabolic process;
fructose
metabolic process;
fructose
1,
6
-bisphosphate metabolic process; sucrose biosynthetic process; Belongs to the FBPase class 1 family.
[a.k.a. FBgn0032820, fbp-PF, fbp-PD]
8)
Saccharomyces cerevisiae
UBP14 - Ubiquitin carboxyl-terminal hydrolase 14; Ubiquitin-specific protease; specifically disassembles unanchored ubiquitin chains; involved in
fructose
-1
,
6
-
bisphosphatase
(Fbp1p) degradation; similar to human isopeptidase T; Belongs to the peptidase C19 family.
[a.k.a. YBR058C, Ubiquitin-specific-processing protease 14, YBR0515]
9)
Saccharomyces cerevisiae
VID24 - Vacuolar import and degradation protein 24; GID Complex regulatory subunit; binds GID Complex in response to glucose through interactions with complex member Vid28p; regulates
fructose
-1
,
6
-
bisphosphatase
(FBPase) targeting to the vacuole; promotes proteasome-dependent catabolite degradation of FBPase; peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; Belongs to the GID4/VID24 family.
[a.k.a. YBR105C, sce:YBR105C, GID4]
10)
Saccharomyces cerevisiae
GID7 - Glucose-induced degradation protein 7; Subunit of GID Complex that binds directly to central component Vid30p; GID complex is involved in proteasome-dependent catabolite inactivation of
fructose
-1
,
6
-
bisphosphatase
; Gid7p contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions.
[a.k.a. YCL039W, NM_001178684.1, CAA42377.1]
11)
Saccharomyces cerevisiae
YDL176W - Uncharacterized protein YDL176W; Protein of unknown function; predicted by computational methods to be involved in
fructose
-1
,
6
-
bisphosphatase
(Fbp1p) degradation; interacts with components of the GID complex; YDL176W is not an essential gene.
[a.k.a. sce:YDL176W, NP_010105, S000002335]
12)
Saccharomyces cerevisiae
RMD5 - E3 ubiquitin-protein ligase RMD5; Component of GID Complex that confers ubiquitin ligase (U3) activity; necessary for polyubiquitination and degradation of the gluconeogenic enzyme
fructose
-1
,
6
-
bisphosphatase
; forms dimer with Fyv10p that is then recruited to GID Complex by Gid8p; also required for sporulation; conserved protein that has a degenerate RING finger domain.
[a.k.a. YDR255C, YD9320A.05c, GID2]
13)
Saccharomyces cerevisiae
UBC8 - Ubiquitin-conjugating enzyme that regulates gluconeogenesis; negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of
fructose
-1
,
6
-
bisphosphatase
(FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro.
[a.k.a. YEL012W, Ubiquitin-protein ligase, NP_010904]
14)
Saccharomyces cerevisiae
VID28 - Vacuolar import and degradation protein 28; GID Complex subunit, serves as adaptor for regulatory subunit Vid24p; protein involved in proteasome-dependent catabolite degradation of
fructose
-1
,
6
-
bisphosphatase
(FBPase); localized to the nucleus and the cytoplasm.
[a.k.a. YIL017C, YIL017W, GID5]
15)
Saccharomyces cerevisiae
VID22 - Vacuolar import and degradation protein 22; Glycosylated integral membrane protein localized to plasma membrane; plays a role in
fructose
-1
,
6
-
bisphosphatase
(FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles; VID22 has a paralog, ENV11, that arose from the whole genome duplication.
[a.k.a. YLR373C, S000004365, YLR373C_mRNA]
16)
Saccharomyces cerevisiae
FBP1 -
Fructose
-1
,
6
-
bisphosphatase
; key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; glucose starvation results in redistribution to the periplasm; interacts with Vid30p; Belongs to the FBPase class 1 family.
[a.k.a. YLR377C, NP_013481, 4932.YLR377C,
Fructose-1,6-bisphosphatase
]
17)
Saccharomyces cerevisiae
GID8 - Glucose-induced degradation protein 8; Subunit of GID Complex, binds strongly to central component Vid30p; GID Complex is involved in proteasome-dependent catabolite inactivation of
fructose
-1
,
6
-
bisphosphatase
; recruits Rmd5p, Fyv10 and Vid28p to GID Complex; contains LisH, CTLH, and CRA domains that mediate binding to Vid30p (LisH) and Rmd5p and Vid28p (CTLH and CRA); dosage-dependent regulator of START.
[a.k.a. YMR135C, GID8_YEAST, CAA87349.1]
18)
Saccharomyces cerevisiae
VID27 - Vacuolar import and degradation protein 27; Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of
fructose
-1
,
6
-
bisphosphatase
(FBPase); null mutants exhibit normal growth; contains two PH-like domains.
[a.k.a. YNL212W, CAA55496.1, S000005156]
19)
Acaryochloris marina
fbp -
Fructose
-1
,
6
-
bisphosphatase
.
[a.k.a. AM1_2875, ABW27874.1, ABW27874,
fructose-1,6-bisphosphatase
,
Fructose-1,6-bisphosphatase
, ...]
20)
Acaryochloris marina
fbp-2 -
Fructose
-1
,
6
-
bisphosphatase
.
[a.k.a. AM1_6321, ABW31251.1, NC_009925.1,
fructose-1,6-bisphosphatase
,
Fructose-1,6-bisphosphatase
, ...]
6328 matches
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