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phzG1 phzG1 phzG2 phzG2 PA1906 PA1906 phzE1 phzE1 phzF1 phzF1 phzS phzS phzD1 phzD1 phzC1 phzC1 phzA1 phzA1 pdxJ pdxJ phzB1 phzB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
phzG1Probable pyridoxamine 5'-phosphate oxidase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (214 aa)    
Predicted Functional Partners:
phzG2
Probable pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
  
 
 
0.901
PA1906
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.769
phzE1
Phenazine biosynthesis protein PhzE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
     
 0.725
phzF1
Probable phenazine biosynthesis protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
    0.705
phzS
Flavin-containing monooxygenase; Involved in the biosynthesis of pyocyanine, a blue-pigmented phenazine derivative, which plays a role in virulence. Catalyzes the oxidative decarboxylation of 5-methylphenazine-1-carboxylate (5-methyl- PCA) to pyocyanine. Can also act on phenazine-1-carboxylate (PCA), converting it into 1-hydroxyphenazine (1-HP). However, PCA is a poor substrate.
 
   
 0.693
phzD1
Phenazine biosynthesis protein PhzD; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
       0.676
phzC1
Phenazine biosynthesis protein PhzC; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
       0.665
phzA1
Probable phenazine biosynthesis protein; Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule. PhzA1 (operon phzA1B1C1E1F1G1) has a role in the biosynthesis of the phenazine during planktonic growth.
     
 0.660
pdxJ
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
  
  
 0.639
phzB1
Probable phenazine biosynthesis protein; Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule. PhzB1 (operon phzA1B1C1E1F1G1) has a role in the biosynthesis of the phenazine during planktonic growth; Belongs to the PhzA/PhzB family.
       0.607
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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