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phzH phzH PA3459 PA3459 pyrB pyrB argG argG purA purA PA2084 PA2084 ansB ansB ansA ansA phzM phzM aspA aspA nadB nadB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phzHPotential phenazine-modifying enzyme; Product name confidence: Class 2 (High similarity to functionally studied protein). (610 aa)    
Predicted Functional Partners:
PA3459
Probable glutamine amidotransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 
0.926
pyrB
Aspartate carbamoyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.917
argG
Argininosuccinate synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 0.916
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.915
PA2084
Probable asparagine synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
0.909
ansB
Glutaminase-asparaginase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the asparaginase 1 family.
     
 0.907
ansA
Product name confidence: Class 2 (High similarity to functionally studied protein).
     
 0.907
phzM
Probable phenazine-specific methyltransferase; Involved in the biosynthesis of pyocyanine, a blue-pigmented phenazine derivative, which plays a role in virulence. Converts phenazine-1-carboxylate (PCA) to 5-methylphenazine-1-carboxylate (5- methyl-PCA); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
 
  
 0.905
aspA
Aspartate ammonia-lyase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.
     
 0.902
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.900
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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