STRINGSTRING
proE proE rpoC rpoC rpoB rpoB cheR cheR rpoA rpoA rseC rseC topA topA DTL3_1480 DTL3_1480 fliI fliI fliM fliM fliE fliE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proERNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.915
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.902
cheR
Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; High confidence in function and specificity.
    
   0.864
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.857
rseC
Represents a positive regulator of the sigma(E) transcription factor; regulates the expression of genes that are collectively termed ECF (devoted to Extra-Cellular Functions); Family membership.
  
  
 0.829
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.782
DTL3_1480
Putative membrain protein; Function unknown; Hypothetical protein.
       0.773
fliI
Flagellum-specific ATP synthase; High confidence in function and specificity.
    
 
 0.771
fliM
Flagellar motor switch protein FliM; High confidence in function and specificity.
    
   0.619
fliE
fliE is a component of the flagellar hook-basal body complex located possibly at (MS-ring)-rod junction; Family membership.
    
   0.619
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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