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YPO0404 YPO0404 YPO0403 YPO0403 YPO0405 YPO0405 fpk fpk fpr-2 fpr-2 YPO0402 YPO0402 mtlA mtlA ptsN ptsN ptsI ptsI nagE nagE fruA fruA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YPO0404PTS system, IIC component; Similar to many carbohydrate phosphotransferase IIC components e.g. part of Escherichia coli PTS system,fructose-specific IIBC component FruA SW:PTFB_ECOLI (P20966) (563 aa) fasta scores: E(): 0, 40.7% id in 329 aa and to Escherichia coli PTS system, fructose-like-2 IIC component FrwC SW:PTWC_ECOLI (P32672) (359 aa) fasta scores: E(): 0, 76.5% id in 358 aa. (361 aa)    
Predicted Functional Partners:
YPO0403
PTS system, IIB component; Similar to many carbohydrate phosphotransferase IIB components e.g. Escherichia coli PTS system,fructose-like-2 IIB component 1 FrwB, SW:PTWB_ECOLI (P32673) (106 aa) fasta scores: E(): 0, 82.7% id in 104 aa. Similar to part of Rhodobacter capsulatus PTS system,fructose-specific IIBC component FruA SW:PTFB_RHOCA (P23387) (578 aa) fasta scores: E(): 6.3e-16, 47.4% id in 97 aa and to Escherichia coli PTS system, fructose-specific IIBC component FruA, PtsF, SW:PTFB_ECOLI (P20966) (563 aa) fasta scores: E(): 1e-15, 49.5% id in 97 aa.
 
 0.991
YPO0405
Similar to e.g. Escherichia coli phosphoenolpyruvate-protein phosphotransferase PtsI,SW:PT1_ECOLI (P08839) (575 aa) fasta scores: E(): 0, 36.0% id in 583 aa, but has both N- and C-terminal extensions. Also similar to Escherichia coli phosphoenolpyruvate-protein phosphotransferase PtsA,SW:PT1A_ECOLI (P32670) (711 aa) fasta scores: E(): 0, 64.5% id in 726 aa and to Escherichia coli putative phosphoenolpyruvate-protein phosphotransferase YpdD,SW:YPDD_ECOLI (P77439) (831 aa) fasta scores: E(): 0, 41.5% id in 853 aa.
 
 
 0.984
fpk
1-phosphofructokinase; Similar to Escherichia coli 1-phosphofructokinase FruK or Fpk SW:K1PF_ECOLI (P23539) (312 aa) fasta scores: E(): 0, 92.0% id in 312 aa, and to Haemophilus influenzae 1-phosphofructokinase FruK SW:K1PF_HAEIN (P44330) (313 aa) fasta scores: E(): 0, 55.4% id in 305 aa; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.982
fpr-2
Fpr protein; Similar to Salmonella typhimurium PTS system,fructose-specific IIa/FPr component FruB SW:PTFA_SALTY (P17127) (376 aa) fasta scores: E(): 0, 71.0% id in 376 aa,and to Escherichia coli PTS system, fructose-specific IIa/FPr component FruB SW:PTFA_ECOLI (P24217) (376 aa) fasta scores: E(): 0, 69.4% id in 376 aa.
 
 0.979
YPO0402
PTS system, IIB component; Similar to many carbohydrate phosphotransferase system IIB components e.g. Escherichia coli PTS system,fructose-like-2 IIB component 2 FrwD SW:PTWX_ECOLI (P32676) (113 aa) fasta scores: E(): 3.2e-23, 52.7% id in 110 aa.
 
 
 0.890
mtlA
Similar to Escherichia coli PTS system,mannitol-specific IIABC component MtlA SW:PTMA_ECOLI (P00550) (637 aa) fasta scores: E(): 0, 81.7% id in 638 aa,and to Klebsiella pneumoniae PTS system, mannitol-specific IIABC component MtlA SW:PTMA_KLEPN (Q9XBM7) (635 aa) fasta scores: E(): 0, 81.1% id in 635 aa.
 
 
 0.844
ptsN
Probable sigma (54) modulation protein (pseudogene); Pfam match to entry PF02482 Ribosomal_S30, score 45.80, E-value 9.7e-10.
 
 
 0.753
ptsI
PTS sytem, enzyme I component; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.748
nagE
Similar to Escherichia coli PTS system,N-acetylglucosamine-specific IIABC component NagE SW:PTAA_ECOLI (P09323) (648 aa) fasta scores: E(): 0, 52.6% id in 683 aa, and to Vibrio furnissii PTS permease for N-acetylglucosamine and glucose NagE TR:P96161 (EMBL:U65014) (496 aa) fasta scores: E(): 0, 69.9% id in 495 aa.
   
 
 0.738
fruA
Similar to Escherichia coli PTS system,fructose-specific IIBC component FruA or PtsF SW:PTFB_ECOLI (P20966) (563 aa) fasta scores: E(): 0, 77.2% id in 569 aa,and to Vibrio cholerae PTS system, fructose-specific IIBC component VCA0516 TR:Q9KM72 (EMBL:AE004382) (580 aa) fasta scores: E(): 0, 65.7% id in 531 aa.
 
 
0.667
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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