Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
There are several matches for 'retS'.
Please select one from the list below and press Continue to proceed.
<- Back
Continue ->
3478 matches
showing page 1 of 174
•
first
•
previous
•
next
•
last
organism
protein
1)
Homo sapiens
DOK5 - Docking protein 5; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in
RET
-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of
RET
in neuronal differentiation.
[a.k.a. ENST00000371403, Q9P104, NX_Q9P104]
2)
Homo sapiens
CD2AP - CD2-associated protein; Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of
RET
turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of
RET
degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glom [...]
[a.k.a. ENST00000479857, 4X1V, 4WCI]
3)
Homo sapiens
ARTN - Artemin; Ligand for the GFR-alpha-3-
RET
receptor complex but can also activate the GFR-alpha-1-
RET
receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.
[a.k.a. EAX07079.1, R-HSA-162582, 2GYR]
4)
Homo sapiens
GFRA2 - GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the
RET
receptor. Also able to mediate GDNF signaling through the
RET
tyrosine kinase receptor; Belongs to the GDNFR family.
[a.k.a. 6Q2O, hsa:2675, AAP88378.1]
5)
Homo sapiens
DOK4 - Docking protein 4; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in
RET
-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of
RET
in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
[a.k.a. NM_001369621.1, XM_024450347.1, ENST00000566705.5]
6)
Homo sapiens
RFPL3 -
Ret
finger protein-like 3; (Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex.
[a.k.a. CAA09046.1, CAG30450.1, AL021937]
7)
Homo sapiens
GFRA3 - GDNF family receptor alpha-3; Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the
RET
receptor tyrosine kinase.
[a.k.a. GDNFR3, R-HSA-162582, GFRA3_HUMAN]
8)
Homo sapiens
CASP3 - Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through
RET
cleavage.
[a.k.a. ENST00000523916, EAX04673.1, 2XZD]
9)
Homo sapiens
GFRA4 - GDNF family receptor alpha-4; Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the
RET
receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
[a.k.a. ENSG00000125861, R-HSA-162582, CCDS13056]
10)
Homo sapiens
GFRAL - GDNF family receptor alpha-like; Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with
RET
and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. Belongs to the GDNFR family.
[a.k.a. NP_997293, GRAL, NM_207410]
11)
Homo sapiens
RFPL4AL1 -
Ret
finger protein like 4A like 1.
[a.k.a. NP_001264326.1, NP_001264326, RFAL1_HUMAN]
12)
Homo sapiens
RFPL1 -
Ret
finger protein-like 1; Negatively regulates the G2-M phase transition, possibly by promoting cyclin B1/CCNB1 and CDK1 proteasomal degradation and thereby preventing their accumulation during interphase.
[a.k.a. ret finger protein like 1, Ret finger protein like 1, ENST00000248980]
13)
Homo sapiens
GFRA1 - GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the
RET
receptor (By similarity).
[a.k.a. NM_145793.5, HGNC:4243, NP_005255.1]
14)
Homo sapiens
RET - Extracellular cell-membrane anchored
RET
cadherin 120 kDa fragment; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. Phosphorylates PTK2/FAK1. Regulates both cell death/survival balance and positional information. Required for the molecular mechanisms orchestration during intestine organogenesis; involved in the development of enteric nervous system and renal organogenesis during embryonic life, and [...]
[a.k.a. MEN2B, ENSP00000327108, NM_020975]
15)
Homo sapiens
DOK6 - Docking protein 6; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes
Ret
-mediated neurite growth. May have a role in brain development and/or maintenance.
[a.k.a. XP_011524177, NP_689934.2, uc002lkl.4]
16)
Homo sapiens
RFPL2 -
Ret
finger protein like 2.
[a.k.a. NM_006605, 10739, NM_001098527.2]
17)
Homo sapiens
KIF26A - Kinesin-like protein KIF26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-
Ret
signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF26 subfamily.
[a.k.a. Q9ULI4, NM_015656.1, ENST00000423312.6]
18)
Homo sapiens
RFPL4A -
Ret
finger protein like 4A.
[a.k.a. Ret finger protein like 4A, ENST00000434937, ret finger protein-like 4]
19)
Homo sapiens
PTPRJ - Receptor-type tyrosine-protein phosphatase eta; Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET,
RET
(variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF- stimulated cell [...]
[a.k.a. R-HSA-6807004, R-HSA-6806834, NM_002843]
20)
Homo sapiens
RFPL4B -
Ret
finger protein like 4B.
[a.k.a. BC132796, ENSG00000251258, AAI32797.1]
3478 matches
showing page 1 of 174
•
first
•
previous
•
next
•
last
<- Back
Continue ->