STRINGSTRING
AZIN2 AZIN2 AGMAT AGMAT ARG2 ARG2 ARG1 ARG1 GATM GATM NOS3 NOS3 NOS1 NOS1 NOS2 NOS2 ASL ASL OAZ2 OAZ2 OAZ3 OAZ3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AZIN2Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (459 aa)    
Predicted Functional Partners:
AGMAT
Agmatinase; Belongs to the arginase family.
  
 
 0.980
ARG2
Arginase.
  
 
 0.974
ARG1
Arginase-1.
  
 
 0.971
GATM
Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development (By similarity).
   
 
 0.958
NOS3
Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity).
     
 0.944
NOS1
Nitric oxide synthase 1.
     
 0.911
NOS2
Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...]
     
 0.908
ASL
Argininosuccinate lyase isoform 1.
  
 
 0.899
OAZ2
Ornithine decarboxylase antizyme 2.
    
 
 0.841
OAZ3
Ornithine decarboxylase antizyme 3.
    
 
 0.786
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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