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There are several matches for 'shc'.
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1535 matches
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organism
protein
1)
Drosophila melanogaster
Shc
-
SHC
-adaptor protein (
Shc
) encodes a protein involved in receptor tyrosine kinase signalling. It regulates anti-parasitoid immune response and tracheal development.
2)
Homo sapiens
SHC1 -
SHC
-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, [...]
[a.k.a. SHC-transforming protein 1, XP_024304851.1, R-HSA-9026519,
SHC
]
3)
Mus musculus
Shc1 -
SHC
-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity). Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p47Shc and isoform p52Shc, once phosphorylated, couple activated receptor kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. [...]
[a.k.a. SHC-transforming protein 1, Q8K4C7, ENSMUST00000146306.1,
Shc
]
4)
Homo sapiens
SHCBP1 -
SHC
SH2 domain-binding protein 1; May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of
Shc
. Acts as a positive regulator of FGF signaling in neural progenitor cells.
[a.k.a. URS0000E97C7F, NP_001311247, SHCBP1-206]
5)
Homo sapiens
SHC2 -
SHC
-transforming protein 2; Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons (By similarity).
[a.k.a. SHC adaptor protein 2, AB001451, R-HSA-162582]
6)
Homo sapiens
INSR - Insulin receptor subunit alpha; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4),
SHC
, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosine residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lea [...]
[a.k.a. R-HSA-9006925, M27197, BAD92098.1]
7)
Homo sapiens
SHC4 -
SHC
-transforming protein 4; Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
[a.k.a. SHC adaptor protein 4, AY358250, ENST00000557797]
8)
Homo sapiens
GRAP2 - GRB2-related adapter protein 2; Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated
shc
.
[a.k.a. AJ011736, GRID, NP_001278757.1]
9)
Homo sapiens
SHC3 -
SHC
-transforming protein 3; Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
[a.k.a. 53358, R-HSA-162582, ENST00000375835.8]
10)
Homo sapiens
KIF26A - Kinesin-like protein KIF26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to
SHC
, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF26 subfamily.
[a.k.a. Q9ULI4, NM_015656.1, ENST00000423312.6]
11)
Acaryochloris marina
shc
- Squalene-hopene cyclase.
12)
Acetobacter ghanensis
shc
- Squalene-hopene cyclase.
13)
Acetobacter tropicalis
Shc
- Squalene--hopene cyclase.
14)
Acidithiobacillus ferrooxidans
shc
- Squalene-hopene cyclase; Identified by similarity to SP:P33990; match to protein family HMM PF00432; match to protein family HMM TIGR01507; match to protein family HMM TIGR01787.
15)
Acidithiobacillus thiooxidans
shc
- Squalene--hopene cyclase.
16)
Acidobacterium capsulatum
shc
- Squalene-hopene cyclase; Identified by similarity to SP:P33247; similarity to GB:BAA25185.1; match to protein family HMM PF00432; match to protein family HMM TIGR01507; match to protein family HMM TIGR01787.
17)
Actinomadura chibensis
shc
- Unannotated protein.
18)
Actinopolyspora mortivallis
shc
- Unannotated protein.
19)
Afipia felis
shc
- Squalene--hopene cyclase.
20)
Afipia massiliensis
shc
- Squalene--hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
1535 matches
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