node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ampDh2 | mltD | PA5485 | PA1812 | AmpDh2; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Membrane-bound lytic murein transglycosylase D precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.512 |
ampDh2 | mltF | PA5485 | PA3764 | AmpDh2; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. | 0.587 |
ampDh2 | rlpA | PA5485 | PA4000 | AmpDh2; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. | 0.611 |
ampDh2 | rlpA-2 | PA5485 | PA4485 | AmpDh2; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.691 |
ampDh2 | sltB1 | PA5485 | PA4001 | AmpDh2; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Soluble lytic transglycosylase B; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.783 |
ampDh3 | mltD | PA0807 | PA1812 | AmpDh3; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Membrane-bound lytic murein transglycosylase D precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.557 |
ampDh3 | mltF | PA0807 | PA3764 | AmpDh3; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. | 0.589 |
ampDh3 | rlpA | PA0807 | PA4000 | AmpDh3; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. | 0.616 |
ampDh3 | rlpA-2 | PA0807 | PA4485 | AmpDh3; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.702 |
ampDh3 | sltB1 | PA0807 | PA4001 | AmpDh3; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Soluble lytic transglycosylase B; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.781 |
dacC | mltD | PA3999 | PA1812 | D-ala-D-ala-carboxypeptidase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the peptidase S11 family. | Membrane-bound lytic murein transglycosylase D precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.568 |
dacC | pbpA | PA3999 | PA4003 | D-ala-D-ala-carboxypeptidase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the peptidase S11 family. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. | 0.922 |
dacC | rlpA | PA3999 | PA4000 | D-ala-D-ala-carboxypeptidase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the peptidase S11 family. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. | 0.666 |
dacC | rodA | PA3999 | PA4002 | D-ala-D-ala-carboxypeptidase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the peptidase S11 family. | Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.829 |
dacC | sltB1 | PA3999 | PA4001 | D-ala-D-ala-carboxypeptidase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the peptidase S11 family. | Soluble lytic transglycosylase B; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.799 |
mltD | ampDh2 | PA1812 | PA5485 | Membrane-bound lytic murein transglycosylase D precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | AmpDh2; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.512 |
mltD | ampDh3 | PA1812 | PA0807 | Membrane-bound lytic murein transglycosylase D precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | AmpDh3; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.557 |
mltD | dacC | PA1812 | PA3999 | Membrane-bound lytic murein transglycosylase D precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | D-ala-D-ala-carboxypeptidase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the peptidase S11 family. | 0.568 |
mltD | mltF | PA1812 | PA3764 | Membrane-bound lytic murein transglycosylase D precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | Conserved hypothetical protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. | 0.954 |
mltD | mltG | PA1812 | PA2963 | Membrane-bound lytic murein transglycosylase D precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.945 |