Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANS86183.1 | ANS86184.1 | VSVS12_02423 | VSVS12_02424 | Belongs to the UPF0125 (RnfH) family. | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | 0.898 |
| ANS86183.1 | smpB | VSVS12_02423 | VSVS12_02425 | Belongs to the UPF0125 (RnfH) family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.569 |
| ANS86184.1 | ANS86183.1 | VSVS12_02424 | VSVS12_02423 | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | Belongs to the UPF0125 (RnfH) family. | 0.898 |
| ANS86184.1 | ANS86333.1 | VSVS12_02424 | VSVS12_02577 | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | Stringent starvation protein; Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme; Belongs to the GST superfamily. HSP26 family; Contains 1 GST C-terminal domain; Contains 1 GST N-terminal domain. | 0.487 |
| ANS86184.1 | dnaQ | VSVS12_02424 | VSVS12_00890 | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | DNA-directed DNA polymerase; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.408 |
| ANS86184.1 | smpB | VSVS12_02424 | VSVS12_02425 | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.577 |
| ANS86184.1 | ubiG | VSVS12_02424 | VSVS12_01820 | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | 2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.520 |
| ANS86184.1 | ubiI | VSVS12_02424 | VSVS12_02662 | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | 2-octaprenylphenol hydroxylase; FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy- phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis; Belongs to the UbiH/COQ6 family; KEGG: vvu:VV1_1553 2-octaprenylphenol hydroxylase; With NADH or NADPH as one donor, and incorporation of one atom of oxygen. | 0.449 |
| ANS86333.1 | ANS86184.1 | VSVS12_02577 | VSVS12_02424 | Stringent starvation protein; Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme; Belongs to the GST superfamily. HSP26 family; Contains 1 GST C-terminal domain; Contains 1 GST N-terminal domain. | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | 0.487 |
| ANS86333.1 | ubiI | VSVS12_02577 | VSVS12_02662 | Stringent starvation protein; Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme; Belongs to the GST superfamily. HSP26 family; Contains 1 GST C-terminal domain; Contains 1 GST N-terminal domain. | 2-octaprenylphenol hydroxylase; FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy- phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis; Belongs to the UbiH/COQ6 family; KEGG: vvu:VV1_1553 2-octaprenylphenol hydroxylase; With NADH or NADPH as one donor, and incorporation of one atom of oxygen. | 0.525 |
| dnaQ | ANS86184.1 | VSVS12_00890 | VSVS12_02424 | DNA-directed DNA polymerase; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | 0.408 |
| smpB | ANS86183.1 | VSVS12_02425 | VSVS12_02423 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Belongs to the UPF0125 (RnfH) family. | 0.569 |
| smpB | ANS86184.1 | VSVS12_02425 | VSVS12_02424 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | 0.577 |
| ubiG | ANS86184.1 | VSVS12_01820 | VSVS12_02424 | 2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | 0.520 |
| ubiG | ubiI | VSVS12_01820 | VSVS12_02662 | 2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 2-octaprenylphenol hydroxylase; FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy- phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis; Belongs to the UbiH/COQ6 family; KEGG: vvu:VV1_1553 2-octaprenylphenol hydroxylase; With NADH or NADPH as one donor, and incorporation of one atom of oxygen. | 0.976 |
| ubiI | ANS86184.1 | VSVS12_02662 | VSVS12_02424 | 2-octaprenylphenol hydroxylase; FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy- phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis; Belongs to the UbiH/COQ6 family; KEGG: vvu:VV1_1553 2-octaprenylphenol hydroxylase; With NADH or NADPH as one donor, and incorporation of one atom of oxygen. | Persistence and stress-resistance toxin PasT; Toxic component of a toxin-antitoxin (TA) module. Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes (By similarity). In this strain of E. coli low levels of PasT complement operon disruption, however high levels are toxi; their effects are abrogated by high level expression of cognate antitoxin PasI. Plays a role in persistence after antibiotic exposure and survival of nitrosative stres; the toxic and persistence phenotypes are conferred by the same N- terminal region of the protein, w [...] | 0.449 |
| ubiI | ANS86333.1 | VSVS12_02662 | VSVS12_02577 | 2-octaprenylphenol hydroxylase; FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy- phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis; Belongs to the UbiH/COQ6 family; KEGG: vvu:VV1_1553 2-octaprenylphenol hydroxylase; With NADH or NADPH as one donor, and incorporation of one atom of oxygen. | Stringent starvation protein; Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme; Belongs to the GST superfamily. HSP26 family; Contains 1 GST C-terminal domain; Contains 1 GST N-terminal domain. | 0.525 |
| ubiI | ubiG | VSVS12_02662 | VSVS12_01820 | 2-octaprenylphenol hydroxylase; FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy- phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis; Belongs to the UbiH/COQ6 family; KEGG: vvu:VV1_1553 2-octaprenylphenol hydroxylase; With NADH or NADPH as one donor, and incorporation of one atom of oxygen. | 2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.976 |