node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cog4 | Cog6 | ENSMUSP00000034203 | ENSMUSP00000048603 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | 0.998 |
Cog4 | Cog8 | ENSMUSP00000034203 | ENSMUSP00000093173 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | 0.997 |
Cog4 | Stx16 | ENSMUSP00000034203 | ENSMUSP00000085218 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | 0.907 |
Cog4 | Stx6 | ENSMUSP00000034203 | ENSMUSP00000027743 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. | 0.844 |
Cog4 | Vps51 | ENSMUSP00000034203 | ENSMUSP00000025711 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | Vacuolar protein sorting-associated protein 51 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome- derived carriers to the TGN. Acts as component of the EARP complex [...] | 0.854 |
Cog4 | Vps52 | ENSMUSP00000034203 | ENSMUSP00000025178 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | Vacuolar protein sorting-associated protein 52 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4- positive endosomes and promotes recycling of internalized t [...] | 0.828 |
Cog4 | Vps53 | ENSMUSP00000034203 | ENSMUSP00000061317 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4- positive endosomes and promotes recycling of internalized t [...] | 0.911 |
Cog4 | Vps54 | ENSMUSP00000034203 | ENSMUSP00000006221 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | Vacuolar protein sorting-associated protein 54; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling. | 0.884 |
Cog6 | Cog4 | ENSMUSP00000048603 | ENSMUSP00000034203 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | 0.998 |
Cog6 | Cog8 | ENSMUSP00000048603 | ENSMUSP00000093173 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | 0.999 |
Cog6 | Stx16 | ENSMUSP00000048603 | ENSMUSP00000085218 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | 0.902 |
Cog6 | Stx6 | ENSMUSP00000048603 | ENSMUSP00000027743 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. | 0.861 |
Cog6 | Vps51 | ENSMUSP00000048603 | ENSMUSP00000025711 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 51 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome- derived carriers to the TGN. Acts as component of the EARP complex [...] | 0.785 |
Cog6 | Vps52 | ENSMUSP00000048603 | ENSMUSP00000025178 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 52 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4- positive endosomes and promotes recycling of internalized t [...] | 0.877 |
Cog6 | Vps53 | ENSMUSP00000048603 | ENSMUSP00000061317 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4- positive endosomes and promotes recycling of internalized t [...] | 0.906 |
Cog6 | Vps54 | ENSMUSP00000048603 | ENSMUSP00000006221 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 54; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling. | 0.863 |
Cog8 | Cog4 | ENSMUSP00000093173 | ENSMUSP00000034203 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. | 0.997 |
Cog8 | Cog6 | ENSMUSP00000093173 | ENSMUSP00000048603 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | 0.999 |
Cog8 | Stx16 | ENSMUSP00000093173 | ENSMUSP00000085218 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | 0.958 |
Cog8 | Stx6 | ENSMUSP00000093173 | ENSMUSP00000027743 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. | 0.873 |