STRINGSTRING
Spag7 Spag7 Tmem239 Tmem239 Fancm Fancm Platr25 Platr25 Fam160b2 Fam160b2 Gm14409 Gm14409 Gm14418 Gm14418 Gm14322 Gm14322 Gm14325 Gm14325 Gm14412 Gm14412 Gm14326 Gm14326
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spag7Sperm-associated antigen 7. (227 aa)    
Predicted Functional Partners:
Tmem239
Transmembrane protein 239.
      
 0.796
Fancm
Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...]
    
 
 0.679
Platr25
Pluripotency-associated transcript 25.
    
 
 0.672
Fam160b2
Protein FAM160B2.
   
  
 0.655
Gm14409
Predicted gene 14409.
    
 
 0.651
Gm14418
Predicted gene 14322.
    
 
 0.613
Gm14322
Predicted gene 14322.
    
 
 0.613
Gm14325
Predicted gene 14325.
    
 
 0.612
Gm14412
Predicted gene 14412.
    
 
 0.612
Gm14326
Zinc finger protein.
    
 
 0.611
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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