node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ap3b1 | Ap3d1 | ENSMUSP00000022196 | ENSMUSP00000020420 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | AP-3 complex subunit delta-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity). Involved in process of CD8+ T-cell and NK cell degranulation (By similarity). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. | 0.999 |
Ap3b1 | Slc30a3 | ENSMUSP00000022196 | ENSMUSP00000031037 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | 0.841 |
Ap3d1 | Ap3b1 | ENSMUSP00000020420 | ENSMUSP00000022196 | AP-3 complex subunit delta-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity). Involved in process of CD8+ T-cell and NK cell degranulation (By similarity). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | 0.999 |
Ap3d1 | Slc30a3 | ENSMUSP00000020420 | ENSMUSP00000031037 | AP-3 complex subunit delta-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity). Involved in process of CD8+ T-cell and NK cell degranulation (By similarity). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | 0.733 |
Slc30a3 | Ap3b1 | ENSMUSP00000031037 | ENSMUSP00000022196 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | 0.841 |
Slc30a3 | Ap3d1 | ENSMUSP00000031037 | ENSMUSP00000020420 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | AP-3 complex subunit delta-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity). Involved in process of CD8+ T-cell and NK cell degranulation (By similarity). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. | 0.733 |
Slc30a3 | Slc30a6 | ENSMUSP00000031037 | ENSMUSP00000136503 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | 0.840 |
Slc30a3 | Slc30a9 | ENSMUSP00000031037 | ENSMUSP00000124047 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | Zinc transporter 9; Acts as a zinc transporter involved in intracellular zinc homeostasis (By similarity). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt- responsive genes ; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.783 |
Slc30a3 | Slc39a1 | ENSMUSP00000031037 | ENSMUSP00000076012 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | Zinc transporter ZIP1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body (By similarity). Belongs to the ZIP transporter (TC 2.A.5) family. | 0.739 |
Slc30a3 | Slc39a12 | ENSMUSP00000031037 | ENSMUSP00000080911 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | Zinc transporter ZIP12; Acts as a zinc-influx transporter. | 0.715 |
Slc30a3 | Slc39a13 | ENSMUSP00000031037 | ENSMUSP00000107063 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | Zinc transporter ZIP13; Acts as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family. | 0.714 |
Slc30a3 | Slc39a5 | ENSMUSP00000031037 | ENSMUSP00000131736 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | Zinc transporter ZIP5; May play a role in polarized cells by carrying out serosal- to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Seems to play a central role in controlling organismal zinc status. | 0.709 |
Slc30a3 | Slc39a6 | ENSMUSP00000031037 | ENSMUSP00000064667 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | Zinc transporter ZIP6; May act as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family. | 0.715 |
Slc30a3 | Slc39a7 | ENSMUSP00000031037 | ENSMUSP00000025186 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | Zinc transporter SLC39A7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. | 0.738 |
Slc30a6 | Slc30a3 | ENSMUSP00000136503 | ENSMUSP00000031037 | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. | 0.840 |
Slc30a6 | Slc30a9 | ENSMUSP00000136503 | ENSMUSP00000124047 | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | Zinc transporter 9; Acts as a zinc transporter involved in intracellular zinc homeostasis (By similarity). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt- responsive genes ; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.859 |
Slc30a6 | Slc39a1 | ENSMUSP00000136503 | ENSMUSP00000076012 | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | Zinc transporter ZIP1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body (By similarity). Belongs to the ZIP transporter (TC 2.A.5) family. | 0.797 |
Slc30a6 | Slc39a12 | ENSMUSP00000136503 | ENSMUSP00000080911 | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | Zinc transporter ZIP12; Acts as a zinc-influx transporter. | 0.764 |
Slc30a6 | Slc39a13 | ENSMUSP00000136503 | ENSMUSP00000107063 | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | Zinc transporter ZIP13; Acts as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family. | 0.795 |
Slc30a6 | Slc39a5 | ENSMUSP00000136503 | ENSMUSP00000131736 | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | Zinc transporter ZIP5; May play a role in polarized cells by carrying out serosal- to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Seems to play a central role in controlling organismal zinc status. | 0.766 |