node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ddx18 | Ebna1bp2 | ENSMUSP00000001724 | ENSMUSP00000030501 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.982 |
Ddx18 | Gnl2 | ENSMUSP00000001724 | ENSMUSP00000030684 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 0.977 |
Ddx18 | Gnl3 | ENSMUSP00000001724 | ENSMUSP00000047119 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Guanine nucleotide-binding protein-like 3; May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation; Belongs to the TRAFAC class YlqF/YawG GTPase family. | 0.978 |
Ddx18 | Gtpbp4 | ENSMUSP00000001724 | ENSMUSP00000152412 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.997 |
Ddx18 | Mrto4 | ENSMUSP00000001724 | ENSMUSP00000099561 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.993 |
Ddx18 | Nifk | ENSMUSP00000001724 | ENSMUSP00000027626 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.999 |
Ddx18 | Pes1 | ENSMUSP00000001724 | ENSMUSP00000020705 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.997 |
Ddx18 | Rpf2 | ENSMUSP00000001724 | ENSMUSP00000138581 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.989 |
Ddx18 | Rsl1d1 | ENSMUSP00000001724 | ENSMUSP00000113431 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | 0.998 |
Ddx18 | Sdad1 | ENSMUSP00000001724 | ENSMUSP00000031364 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm. | 0.869 |
Ebna1bp2 | Ddx18 | ENSMUSP00000030501 | ENSMUSP00000001724 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | 0.982 |
Ebna1bp2 | Gnl2 | ENSMUSP00000030501 | ENSMUSP00000030684 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 0.960 |
Ebna1bp2 | Gnl3 | ENSMUSP00000030501 | ENSMUSP00000047119 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Guanine nucleotide-binding protein-like 3; May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation; Belongs to the TRAFAC class YlqF/YawG GTPase family. | 0.994 |
Ebna1bp2 | Gtpbp4 | ENSMUSP00000030501 | ENSMUSP00000152412 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.993 |
Ebna1bp2 | Mrto4 | ENSMUSP00000030501 | ENSMUSP00000099561 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.994 |
Ebna1bp2 | Nifk | ENSMUSP00000030501 | ENSMUSP00000027626 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.998 |
Ebna1bp2 | Pes1 | ENSMUSP00000030501 | ENSMUSP00000020705 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
Ebna1bp2 | Rpf2 | ENSMUSP00000030501 | ENSMUSP00000138581 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.996 |
Ebna1bp2 | Rsl1d1 | ENSMUSP00000030501 | ENSMUSP00000113431 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | 0.995 |
Ebna1bp2 | Sdad1 | ENSMUSP00000030501 | ENSMUSP00000031364 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm. | 0.874 |