node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D1025.1 | K10D3.4 | D1025.1.1 | K10D3.4.1 | Uncharacterized protein. | Uncharacterized protein. | 0.851 |
D1025.1 | hmg-1.1 | D1025.1.1 | Y48B6A.14.2 | Uncharacterized protein. | HMG box domain-containing protein. | 0.818 |
K10D3.4 | D1025.1 | K10D3.4.1 | D1025.1.1 | Uncharacterized protein. | Uncharacterized protein. | 0.851 |
K10D3.4 | hmg-1.1 | K10D3.4.1 | Y48B6A.14.2 | Uncharacterized protein. | HMG box domain-containing protein. | 0.807 |
T22C1.1 | hmg-1.1 | T22C1.1.2 | Y48B6A.14.2 | UBR-type domain-containing protein. | HMG box domain-containing protein. | 0.854 |
hmg-1.1 | D1025.1 | Y48B6A.14.2 | D1025.1.1 | HMG box domain-containing protein. | Uncharacterized protein. | 0.818 |
hmg-1.1 | K10D3.4 | Y48B6A.14.2 | K10D3.4.1 | HMG box domain-containing protein. | Uncharacterized protein. | 0.807 |
hmg-1.1 | T22C1.1 | Y48B6A.14.2 | T22C1.1.2 | HMG box domain-containing protein. | UBR-type domain-containing protein. | 0.854 |
hmg-1.1 | hmg-4 | Y48B6A.14.2 | T20B12.8.1 | HMG box domain-containing protein. | FACT complex subunit SSRP1-A; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] | 0.562 |
hmg-1.1 | htz-1 | Y48B6A.14.2 | R08C7.3.3 | HMG box domain-containing protein. | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | 0.755 |
hmg-1.1 | oaz-1 | Y48B6A.14.2 | ZK484.1a.1 | HMG box domain-containing protein. | Ornithine decarboxylase antizyme; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin- independent proteolytic destruction by the 26S proteasome. | 0.743 |
hmg-1.1 | rpl-24.1 | Y48B6A.14.2 | D1007.12.1 | HMG box domain-containing protein. | 60S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family. | 0.716 |
hmg-1.1 | rpl-7A | Y48B6A.14.2 | Y24D9A.4a.1 | HMG box domain-containing protein. | 60S ribosomal protein L7a; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.744 |
hmg-1.1 | rps-12 | Y48B6A.14.2 | F54E7.2.1 | HMG box domain-containing protein. | 40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. | 0.835 |
hmg-1.1 | rps-8 | Y48B6A.14.2 | F42C5.8a.1 | HMG box domain-containing protein. | 40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. | 0.590 |
hmg-4 | hmg-1.1 | T20B12.8.1 | Y48B6A.14.2 | FACT complex subunit SSRP1-A; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] | HMG box domain-containing protein. | 0.562 |
hmg-4 | htz-1 | T20B12.8.1 | R08C7.3.3 | FACT complex subunit SSRP1-A; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | 0.659 |
htz-1 | hmg-1.1 | R08C7.3.3 | Y48B6A.14.2 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | HMG box domain-containing protein. | 0.755 |
htz-1 | hmg-4 | R08C7.3.3 | T20B12.8.1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | FACT complex subunit SSRP1-A; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] | 0.659 |
oaz-1 | hmg-1.1 | ZK484.1a.1 | Y48B6A.14.2 | Ornithine decarboxylase antizyme; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin- independent proteolytic destruction by the 26S proteasome. | HMG box domain-containing protein. | 0.743 |