STRINGSTRING
GOT2 GOT2 MDH2 MDH2 GOT1 GOT1 GPT2 GPT2 GPT GPT KYAT3 KYAT3 TAT TAT MDH1 MDH1 GOT1L1 GOT1L1 HPD HPD FH FH
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GOT2Aspartate aminotransferase. (430 aa)    
Predicted Functional Partners:
MDH2
Malate dehydrogenase.
   
 0.997
GOT1
Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]
  
0.976
GPT2
Glutamic pyruvate transaminase (Alanine aminotransferase) 2.
   
 0.971
GPT
Glutamic--pyruvic transaminase.
   
 0.971
KYAT3
Cysteine conjugate-beta lyase 2.
   
 0.968
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 0.965
MDH1
Malate dehydrogenase.
   
 0.964
GOT1L1
GOT1L1 isoform 1.
  
0.964
HPD
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.963
FH
Fumarate hydratase.
   
 0.958
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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