node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FH | GOT1 | ENSPTRP00000003656 | ENSPTRP00000004968 | Fumarate hydratase. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.949 |
FH | GOT1L1 | ENSPTRP00000003656 | ENSPTRP00000093290 | Fumarate hydratase. | GOT1L1 isoform 1. | 0.949 |
FH | GOT2 | ENSPTRP00000003656 | ENSPTRP00000013976 | Fumarate hydratase. | Aspartate aminotransferase. | 0.958 |
FH | GPT | ENSPTRP00000003656 | ENSPTRP00000039118 | Fumarate hydratase. | Glutamic--pyruvic transaminase. | 0.918 |
FH | GPT2 | ENSPTRP00000003656 | ENSPTRP00000013801 | Fumarate hydratase. | Glutamic pyruvate transaminase (Alanine aminotransferase) 2. | 0.918 |
FH | KYAT3 | ENSPTRP00000003656 | ENSPTRP00000001612 | Fumarate hydratase. | Cysteine conjugate-beta lyase 2. | 0.597 |
FH | MDH1 | ENSPTRP00000003656 | ENSPTRP00000088176 | Fumarate hydratase. | Malate dehydrogenase. | 0.973 |
FH | MDH2 | ENSPTRP00000003656 | ENSPTRP00000033039 | Fumarate hydratase. | Malate dehydrogenase. | 0.995 |
FH | TAT | ENSPTRP00000003656 | ENSPTRP00000014220 | Fumarate hydratase. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.595 |
GOT1 | FH | ENSPTRP00000004968 | ENSPTRP00000003656 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Fumarate hydratase. | 0.949 |
GOT1 | GOT1L1 | ENSPTRP00000004968 | ENSPTRP00000093290 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | GOT1L1 isoform 1. | 0.914 |
GOT1 | GOT2 | ENSPTRP00000004968 | ENSPTRP00000013976 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Aspartate aminotransferase. | 0.976 |
GOT1 | GPT | ENSPTRP00000004968 | ENSPTRP00000039118 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Glutamic--pyruvic transaminase. | 0.962 |
GOT1 | GPT2 | ENSPTRP00000004968 | ENSPTRP00000013801 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Glutamic pyruvate transaminase (Alanine aminotransferase) 2. | 0.960 |
GOT1 | HPD | ENSPTRP00000004968 | ENSPTRP00000009453 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 4-hydroxyphenylpyruvate dioxygenase. | 0.963 |
GOT1 | KYAT3 | ENSPTRP00000004968 | ENSPTRP00000001612 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Cysteine conjugate-beta lyase 2. | 0.943 |
GOT1 | MDH1 | ENSPTRP00000004968 | ENSPTRP00000088176 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Malate dehydrogenase. | 0.968 |
GOT1 | MDH2 | ENSPTRP00000004968 | ENSPTRP00000033039 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Malate dehydrogenase. | 0.986 |
GOT1 | TAT | ENSPTRP00000004968 | ENSPTRP00000014220 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.951 |
GOT1L1 | FH | ENSPTRP00000093290 | ENSPTRP00000003656 | GOT1L1 isoform 1. | Fumarate hydratase. | 0.949 |