Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDX3Y | EIF1AY | ENSP00000353284 | ENSP00000354722 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | 0.999 |
| DDX3Y | KDM5D | ENSP00000353284 | ENSP00000322408 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Lysine-specific demethylase 5D; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity [...] | 0.999 |
| DDX3Y | NLGN4Y | ENSP00000353284 | ENSP00000348169 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Neuroligin-4, Y-linked; Putative neuronal cell surface protein involved in cell-cell- interactions. | 0.864 |
| DDX3Y | PRKY | ENSP00000353284 | ENSP00000498737 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Putative serine/threonine-protein kinase PRKY; Protein kinase Y-linked; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. | 0.923 |
| DDX3Y | RPS4Y1 | ENSP00000353284 | ENSP00000250784 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Ribosomal protein S4 Y-linked 1; Belongs to the eukaryotic ribosomal protein eS4 family. | 0.963 |
| DDX3Y | SRY | ENSP00000353284 | ENSP00000372547 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partia [...] | 0.769 |
| DDX3Y | TMSB4Y | ENSP00000353284 | ENSP00000284856 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Thymosin beta-4, Y-chromosomal; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity); Belongs to the thymosin beta family. | 0.914 |
| DDX3Y | USP9Y | ENSP00000353284 | ENSP00000342812 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | 0.999 |
| DDX3Y | UTY | ENSP00000353284 | ENSP00000442047 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Histone demethylase UTY; Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity. Belongs to the UTX family. | 0.999 |
| DDX3Y | ZFY | ENSP00000353284 | ENSP00000155093 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Zinc finger Y-chromosomal protein; Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3'. | 0.973 |
| EIF1AY | DDX3Y | ENSP00000354722 | ENSP00000353284 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | 0.999 |
| EIF1AY | KDM5D | ENSP00000354722 | ENSP00000322408 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Lysine-specific demethylase 5D; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity [...] | 0.999 |
| EIF1AY | NLGN4Y | ENSP00000354722 | ENSP00000348169 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Neuroligin-4, Y-linked; Putative neuronal cell surface protein involved in cell-cell- interactions. | 0.942 |
| EIF1AY | PRKY | ENSP00000354722 | ENSP00000498737 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Putative serine/threonine-protein kinase PRKY; Protein kinase Y-linked; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. | 0.950 |
| EIF1AY | RPS4Y1 | ENSP00000354722 | ENSP00000250784 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Ribosomal protein S4 Y-linked 1; Belongs to the eukaryotic ribosomal protein eS4 family. | 0.999 |
| EIF1AY | SRY | ENSP00000354722 | ENSP00000372547 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partia [...] | 0.548 |
| EIF1AY | TMSB4Y | ENSP00000354722 | ENSP00000284856 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Thymosin beta-4, Y-chromosomal; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity); Belongs to the thymosin beta family. | 0.898 |
| EIF1AY | USP9Y | ENSP00000354722 | ENSP00000342812 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...] | 0.999 |
| EIF1AY | UTY | ENSP00000354722 | ENSP00000442047 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Histone demethylase UTY; Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity. Belongs to the UTX family. | 0.963 |
| EIF1AY | ZFY | ENSP00000354722 | ENSP00000155093 | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). | Zinc finger Y-chromosomal protein; Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3'. | 0.965 |
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