STRINGSTRING
SMAD5 SMAD5 SMAD4 SMAD4 BMPR1A BMPR1A BMPR1B BMPR1B BMPR2 BMPR2 SMAD7 SMAD7 ACVR1 ACVR1 SMAD9 SMAD9 SMAD1 SMAD1 SMAD6 SMAD6 MAPK1 MAPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD5Mothers against decapentaplegic homolog. (465 aa)    
Predicted Functional Partners:
SMAD4
Mothers against decapentaplegic homolog.
   
0.997
BMPR1A
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.974
BMPR1B
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.973
BMPR2
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.972
SMAD7
Mothers against decapentaplegic homolog.
   
0.962
ACVR1
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.962
SMAD9
Mothers against decapentaplegic homolog.
  
0.947
SMAD1
Mothers against decapentaplegic homolog.
  
 
0.937
SMAD6
Mothers against decapentaplegic homolog.
   
0.936
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.915
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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